KEGG   ENZYME: 1.5.1.37Help
Entry
EC 1.5.1.37                 Enzyme                                 

Name
FAD reductase (NADH);
NADH-FAD reductase;
NADH-dependent FAD reductase;
NADH:FAD oxidoreductase;
NADH:flavin adenine dinucleotide oxidoreductase
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
FADH2:NAD+ oxidoreductase
Reaction(IUBMB)
FADH2 + NAD+ = FAD + NADH + H+ [RN:R09748]
Reaction(KEGG)
Substrate
FADH2 [CPD:C01352];
NAD+ [CPD:C00003]
Product
FAD [CPD:C00016];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme from Burkholderia phenoliruptrix can reduce either FAD or flavin mononucleotide (FMN) but prefers FAD. Unlike EC 1.5.1.36, flavin reductase (NADH), the enzyme can not reduce riboflavin. The enzyme does not use NADPH as acceptor.
History
EC 1.5.1.37 created 2011
Pathway
Riboflavin metabolism
Microbial metabolism in diverse environments
Orthology
K15245  
chlorophenol-4-monooxygenase component 1
Reference
1  [PMID:12700257]
  Authors
Gisi MR, Xun L
  Title
Characterization of chlorophenol 4-monooxygenase (TftD) and NADH:flavin adenine dinucleotide oxidoreductase (TftC) of Burkholderia cepacia AC1100.
  Journal
J. Bacteriol. 185 (2003) 2786-92.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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