KEGG   ENZYME: 1.5.1.40Help
Entry
EC 1.5.1.40                 Enzyme                                 

Name
8-hydroxy-5-deazaflavin:NADPH oxidoreductase;
8-OH-5dFl:NADPH oxidoreductase
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
reduced coenzyme F420:NADP+ oxidoreductase
Reaction(IUBMB)
reduced coenzyme F420 + NADP+ = oxidized coenzyme F420 + NADPH + H+ [RN:R09749]
Reaction(KEGG)
Substrate
reduced coenzyme F420 [CPD:C01080];
NADP+ [CPD:C00006]
Product
oxidized coenzyme F420 [CPD:C00876];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme has an absolute requirement for both the 5-deazaflavin structure and the presence of an 8-hydroxy group in the substrate [1].
History
EC 1.5.1.40 created 2011
Reference
1  [PMID:2492438]
  Authors
Eker AP, Hessels JK, Meerwaldt R
  Title
Characterization of an 8-hydroxy-5-deazaflavin:NADPH oxidoreductase from Streptomyces griseus.
  Journal
Biochim. Biophys. Acta. 990 (1989) 80-6.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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