KEGG   ENZYME: 1.5.3.15Help
Entry
EC 1.5.3.15                 Enzyme                                 

Name
N8-acetylspermidine oxidase (propane-1,3-diamine-forming)
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming)
Reaction(IUBMB)
N8-acetylspermidine + O2 + H2O = propane-1,3-diamine + 4-acetamidobutanal + H2O2 [RN:R09075]
Reaction(KEGG)
Substrate
N8-acetylspermidine [CPD:C01029];
O2 [CPD:C00007];
H2O [CPD:C00001]
Product
propane-1,3-diamine [CPD:C00986];
4-acetamidobutanal [CPD:C05936];
H2O2 [CPD:C00027]
Comment
Also active with N1-acetylspermine, weak activity with N1,N12-diacetylspermine. No activity with diaminopropane, putrescine, cadaverine, diaminohexane, norspermidine, spermine and spermidine. Absence of monoamine oxidase (EC 1.4.3.4) activity. Differs in specificity from EC 1.5.3.13 (N1-acetylpolyamine oxidase), EC 1.5.3.14 (polyamine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.16 (spermine oxidase) and EC 1.5.3.17 (non-specific polyamine oxidase).
History
EC 1.5.3.15 created 2009
Reference
1  [PMID:1565141]
  Authors
Shukla OP, Muller S, Walter RD
  Title
Polyamine oxidase from Acanthamoeba culbertsoni specific for N8-acetylspermidine.
  Journal
Mol. Biochem. Parasitol. 51 (1992) 91-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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