KEGG   ENZYME: 1.5.3.7Help
Entry
EC 1.5.3.7                  Enzyme                                 
Name
L-pipecolate oxidase;
pipecolate oxidase;
L-pipecolic acid oxidase
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
L-pipecolate:oxygen 1,6-oxidoreductase
Reaction(IUBMB)
L-pipecolate + O2 = (S)-2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 [RN:R02204]
Reaction(KEGG)
Substrate
L-pipecolate [CPD:C00408];
O2 [CPD:C00007]
Product
(S)-2,3,4,5-tetrahydropyridine-2-carboxylate [CPD:C00450];
H2O2 [CPD:C00027]
Comment
The product reacts with water to form (S)-2-amino-6-oxohexanoate.
Pathway
Lysine degradation
Metabolic pathways
Orthology
K00306  
sarcosine oxidase / L-pipecolate oxidase
Genes
HSA: 
51268(PIPOX)
PTR: 
454541(PIPOX)
PPS: 
100992747(PIPOX)
GGO: 
101145672(PIPOX)
PON: 
100172798(PIPOX)
MCC: 
711090(PIPOX)
MMU: 
19193(Pipox)
RNO: 
303272(Pipox)
CFA: 
491177(PIPOX)
AML: 
FCA: 
101094711(PIPOX)
BTA: 
509102(PIPOX)
SSC: 
100515508
ECB: 
100059605
MDO: 
100025469
SHR: 
100934272
OAA: 
100079754
GGA: 
771808(PIPOX)
MGP: 
100540414
XLA: 
735186(pipox)
XTR: 
548382(pipox)
DRE: 
558601(pipox)
TRU: 
101063029
OLA: 
101160829
BFO: 
BRAFLDRAFT_114735
CIN: 
100177623
SPU: 
591772
GMX: 
100789864
MTR: 
MTR_3g108990 MTR_3g109010
POP: 
POPTR_672574(SOX2)
BDI: 
100834553
 » show all
Taxonomy
Reference
1  [PMID:6051341]
  Authors
Baginsky ML, Rodwell VW.
  Title
Metabolism of pipecolic acid in a Pseudomonas species. V. Pipecolate oxidase and dehydrogenase.
  Journal
J. Bacteriol. 94 (1967) 1034-9.
  Organism
Pseudomonas sp.
Reference
2  [PMID:6809728]
  Authors
Kinzel JJ, Bhattacharjee JK.
  Title
Lysine biosynthesis in Rhodotorula glutinis: properties of pipecolic acid oxidase.
  Journal
J. Bacteriol. 151 (1982) 1073-7.
  Organism
Rhodotorula glutinis
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
81669-65-0
DBGET integrated database retrieval system