| Entry |
|
| Name |
5,10-methylenetetrahydromethanopterin reductase;
5,10-methylenetetrahydromethanopterin cyclohydrolase;
N5,N10-methylenetetrahydromethanopterin reductase;
methylene-H4MPT reductase;
coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase;
N5,N10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase
|
| Class |
Oxidoreductases;
Acting on the CH-NH group of donors;
With other acceptors
 |
| Sysname |
5-methyltetrahydromethanopterin:coenzyme-F420 oxidoreductase
|
| Reaction(IUBMB) |
5-methyltetrahydromethanopterin + coenzyme F420 = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420 [RN: R04464]
|
| Reaction(KEGG) |
|
| Substrate |
5-methyltetrahydromethanopterin [CPD: C04488];
coenzyme F420 [CPD: C00876]
|
| Product |
5,10-methylenetetrahydromethanopterin [CPD: C04377];
reduced coenzyme F420 [CPD: C01080]
|
| Comment |
Catalyses an intermediate step in methanogenesis from CO2 and H2 in bacteria.
|
| Pathway |
| Methane metabolism | | Metabolic pathways | | Microbial metabolism in diverse environments |
|
| Orthology |
| coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase |
|
| Genes |
HOH: | | RPB: | | SWI: | | MAV: | | MSM: | | MJL: | | RHA: | | SRT: | | BCV: | | CFL: | | NCA: | | SRO: | | FAL: | | SEN: | | MAU: | | MIL: | | VMA: | | RXY: | | CWO: | | MJA: | | MFE: | | MVU: | | MFS: | | MIF: | | MIG: | | MMP: | | MMQ: | | MMX: | | MMZ: | | MMD: | | MAE: | | MVN: | | MVO: | | MOK: | | MAC: | | MBA: | | MMA: | | MBU: | | MMH: | | MEV: | | MZH: | | MTP: | | MHU: | | MLA: | | MEM: | | MPI: | | MBN: | | MPL: | | MPD: | | MEZ: | | RCI: | | MTH: | | MMG: | | MST: | | MSI: | | MRU: | | MEL: | | MFV: | | MKA: | | AFU: | | APO: | | FPL: | | HMA: | | HWA: | | NPH: | | HLA: | | HUT: | | HMU: | | HTU: | | NMG: | | HVO: | | HJE: | | HBO: | | HXA: | | » show all
 |
| Reference |
|
| Authors |
Ma K, Thauer RK. |
| Title |
Purification and properties of N5, N10-methylenetetrahydromethanopterin reductase from Methanobacterium thermoautotrophicum (strain Marburg). |
| Journal |
Eur. J. Biochem. 191 (1990) 187-93. |
| Organism |
Methanobacterium thermoautotrophicum [GN: mth] |
| Reference |
|
| Authors |
te Brommelstroet BW, Geerts WJ, Keltjens JT, van der Drift C, Vogels GD. |
| Title |
Purification and properties of 5,10-methylenetetrahydromethanopterin dehydrogenase and 5,10-methylenetetrahydromethanopterin reductase, two coenzyme F420-dependent enzymes, from Methanosarcina barkeri. |
| Journal |
Biochim. Biophys. Acta. 1079 (1991) 293-302. |
| Organism |
Methanosarcina barkeri [GN: mba] |
| Reference |
|
| Authors |
Ma K, Thauer RK. |
| Title |
Single step purification of methylenetetrahydromethanopterin reductase from Methanobacterium thermoautotrophicum by specific binding to blue sepharose CL-6B. |
| Journal |
FEBS. Lett. 268 (1990) 59-62. |
| Organism |
Methanobacterium thermoautotrophicum [GN: mth] |
| Reference |
|
| Authors |
te Brommelstroet BW, Hensgens CM, Keltjens JT, van der Drift C, Vogels GD. |
| Title |
Purification and properties of 5,10-methylenetetrahydromethanopterin reductase, a coenzyme F420-dependent enzyme, from Methanobacterium thermoautotrophicum strain delta H. |
| Journal |
J. Biol. Chem. 265 (1990) 1852-7. |
| Organism |
Methanobacterium thermoautotrophicum [GN: mth] |
| Reference |
|
| Authors |
te Brommelstroet BW, Hensgens CM, Geerts WJ, Keltjens JT, van der Drift C, Vogels GD. |
| Title |
Purification and properties of 5,10-methenyltetrahydromethanopterin cyclohydrolase from Methanosarcina barkeri. |
| Journal |
J. Bacteriol. 172 (1990) 564-71. |
| Organism |
Methanosarcina barkeri [GN: mba] |
| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: UM-BBD (Biocatalysis/Biodegradation Database): BRENDA, the Enzyme Database: |