KEGG   ENZYME: 1.5.99.3Help
Entry
EC 1.5.99.3                 Enzyme                                 
Name
L-pipecolate dehydrogenase;
L-pipecolate:(acceptor) 1,6-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With other acceptors
BRITE hierarchy
Sysname
L-pipecolate:acceptor 1,6-oxidoreductase
Reaction(IUBMB)
L-pipecolate + acceptor = (S)-2,3,4,5-tetrahydropyridine-2-carboxylate + reduced acceptor [RN:R02206]
Reaction(KEGG)
Substrate
L-pipecolate [CPD:C00408];
acceptor [CPD:C00028]
Product
(S)-2,3,4,5-tetrahydropyridine-2-carboxylate [CPD:C00450];
reduced acceptor [CPD:C00030]
Comment
The product reacts with water to form (S)-2-amino-6-oxohexanoate.
Pathway
Lysine degradation
Metabolic pathways
Reference
1  [PMID:6051341]
  Authors
Baginsky ML, Rodwell VW.
  Title
Metabolism of pipecolic acid in a Pseudomonas species. V. Pipecolate oxidase and dehydrogenase.
  Journal
J. Bacteriol. 94 (1967) 1034-9.
  Organism
Pseudomonas sp.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9076-63-5
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