KEGG   ENZYME: 1.6.1.3Help
Entry
EC 1.6.1.3                  Enzyme                                 

Name
NAD(P)+ transhydrogenase;
pyridine nucleotide transhydrogenase;
transhydrogenase (ambiguous);
nicotinamide adenine dinucleotide (phosphate) transhydrogenase (ambiguous);
NAD+ transhydrogenase (ambiguous);
NADH transhydrogenase (misleading);
nicotinamide nucleotide transhydrogenase (ambiguous);
NADPH-NAD+ transhydrogenase (ambiguous);
pyridine nucleotide transferase (ambiguous);
NADPH-NAD+ oxidoreductase (ambiguous);
NADH-NADP+-transhydrogenase (ambiguous);
NADPH:NAD+ transhydrogenase;
H+-Thase (ambiguous);
non-energy-linked transhydrogenase (ambiguous)
Class
Oxidoreductases;
Acting on NADH or NADPH;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
NADPH:NAD+ oxidoreductase
Reaction(IUBMB)
NADPH + NAD+ = NADP+ + NADH [RN:R00112]
Reaction(KEGG)
Substrate
NADPH [CPD:C00005];
NAD+ [CPD:C00003]
Product
NADP+ [CPD:C00006];
NADH [CPD:C00004]
Comment
The enzyme catalyses the NADPH-driven reduction of NAD+. This entry stands for enzymes whose stereo-specificity with respect to NADPH is not known. [cf. EC 1.6.1.1, NAD(P)+ transhydrogenase (Si-specific) and EC 1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific)].
History
EC 1.6.1.3 created 2013
Reference
1  [PMID:13752224]
  Authors
KEISTER DL, SAN PIETRO A, STOLZENBACH FE
  Title
Pyridine nucleotide transhydrogenase from spinach. I. Purification and properties.
  Journal
J. Biol. Chem. 235 (1960) 2989-96.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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