KEGG   ENZYME: 1.6.5.4Help
Entry
EC 1.6.5.4                  Enzyme                                 

Name
monodehydroascorbate reductase (NADH);
NADH:semidehydroascorbic acid oxidoreductase;
MDHA;
semidehydroascorbate reductase;
AFR;
AFR-reductase;
ascorbic free radical reductase;
ascorbate free radical reductase;
SOR;
MDAsA reductase (NADPH) ;
SDA reductase;
NADH:ascorbate radical oxidoreductase;
NADH-semidehydroascorbate oxidoreductase;
ascorbate free-radical reductase ;
NADH:AFR oxidoreductase;
monodehydroascorbate reductase (NADH2)
Class
Oxidoreductases;
Acting on NADH or NADPH;
With a quinone or similar compound as acceptor
BRITE hierarchy
Sysname
NADH:monodehydroascorbate oxidoreductase
Reaction(IUBMB)
NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate [RN:R00095]
Reaction(KEGG)
Substrate
NADH [CPD:C00004];
H+ [CPD:C00080];
monodehydroascorbate [CPD:C01041]
Product
NAD+ [CPD:C00003];
ascorbate [CPD:C00072]
History
EC 1.6.5.4 created 1961
Pathway
Ascorbate and aldarate metabolism
Metabolic pathways
Orthology
K08232  
monodehydroascorbate reductase (NADH)
Genes
ATH: 
AT1G63940(MDAR6) AT3G09940(MDHAR) AT3G27820(MDAR4) AT3G52880(MDAR1) AT5G03630(ATMDAR2)
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POP: 
POPTR_0001s09830g(POPTRDRAFT_815070) POPTR_0001s35220g(POPTRDRAFT_815507) POPTR_0006s11570g
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NNU: 
OSA: 
4330469(49D11.20a) 4344670(OJ1349_D05.106) 4346299(OJ1150_A11.25) 4347885(OJ1155_H10.27)
DOSA: 
Os02t0707000-00(Os02g0707000) Os02t0707100-01(Os02g0707100) Os08t0151800-01(Os08g0151800) Os08t0557600-01(Os08g0557600) Os09t0567300-01(Os09g0567300)
OBR: 
BDI: 
SBI: 
SORBI_04g030440(SORBIDRAFT_04g030440) SORBI_04g030450(SORBIDRAFT_04g030450) SORBI_07g024320(SORBIDRAFT_07g024320)
ZMA: 
100193942 100272772(IDP52) 100279805(uaz204) 100382120(gpm592) 100501585(GRMZM2G084881)
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 » show all
Taxonomy
Reference
1  [PMID:4405497]
  Authors
Schulze HU, Schott HH, Staudinger H.
  Title
[The isolation and characterization of a NADH: semidehydroascorbic acid oxidoreductase from Neurospora crassa]
  Journal
Hoppe. Seylers. Z. Physiol. Chem. 353 (1972) 1931-42.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9029-26-9

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