KEGG   ENZYME: 1.7.1.2Help
Entry
EC 1.7.1.2                  Enzyme                                 

Name
nitrate reductase [NAD(P)H];
assimilatory nitrate reductase;
assimilatory NAD(P)H-nitrate reductase;
NAD(P)H bispecific nitrate reductase;
nitrate reductase (reduced nicotinamide adenine dinucleotide (phosphate));
nitrate reductase NAD(P)H;
NAD(P)H-nitrate reductase;
nitrate reductase [NAD(P)H2];
NAD(P)H2:nitrate oxidoreductase
Class
Oxidoreductases;
Acting on other nitrogenous compounds as donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
nitrite:NAD(P)+ oxidoreductase
Reaction(IUBMB)
nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+ [RN:R00794 R00796]
Reaction(KEGG)
Substrate
nitrite [CPD:C00088];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
nitrate [CPD:C00244];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
An iron-sulfur molybdenum flavoprotein.
History
EC 1.7.1.2 created 1961 as EC 1.6.6.2, transferred 2002 to EC 1.7.1.2
Pathway
ec00910  Nitrogen metabolism
ec01120  Microbial metabolism in diverse environments
Orthology
K10534  nitrate reductase (NAD(P)H)
Genes
ATH: AT1G37130(NIA2) AT1G77760(NIA1)
ALY: ARALYDRAFT_891281 ARALYDRAFT_895665
CRB: 17895831 17897387
CSAT: 104702559 104713453 104742100 104743831 104751674 104757885 104777515
EUS: EUTSA_v10003628mg EUTSA_v10018092mg
BRP: 103830551(NR) 103832206 103853097
BNA: 106353470 106354597 106368948 106397776 106400358 106411852 111210558
BOE: 106300064 106300202 106327343
THJ: 104813138 104813644 104817024
CPAP: 110815200
CIT: 102610866
TCC: 18592259
EGR: 104450466
ADU: 107460801
AIP: 107606095
LJA: Lj0g3v0006719.1(Lj0g3v0006719.1)
FVE: 101295234
PPER: 18790070
PMUM: 103332932
PAVI: 110753196
CSV: 101216001(NR1) 101219000(NR2) 101219242(NR3)
RCU: 8274143(NIA)
JCU: 105638879
HBR: 110647032
POP: 7469126
VVI: 100264320
SLY: 100736473(NR)
SPEN: 107004448
SOT: 102577728(NR3)
CANN: 107867964
INI: 109176053
BVG: 104887841
SOE: 110786500
DOSA: Os02t0770800-01(Os02g0770800) Os08t0468100-01(Os08g0468100) Os08t0468700-00(Os08g0468700)
ATS: 109742560(LOC109742560) 109757553(LOC109757553) 109768384(LOC109768384)
PDA: 103710540
EGU: 105035363
DCT: 110097032
AOF: 109835182
ATR: 18423189
CRE: CHLREDRAFT_184661(NIT1)
VCN: VOLCADRAFT_76569(nitA)
MNG: MNEG_1964
NCR: NCU05298(nit-3)
NTE: NEUTE1DRAFT80350(NEUTE1DRAFT_80350)
MGR: MGG_06062
MAW: MAC_08624
MBE: MBM_01744
ANG: ANI_1_2088064(An07g08910) ANI_1_2090064(An07g08920) ANI_1_802074(An08g05610)
PBL: PAAG_03766 PAAG_12411(PAAG_07727)
PTE: PTT_08192
SMIN: v1.2.036677.t1(symbB.v1.2.036677.t1) v1.2.039611.t1(symbB.v1.2.039611.t1) v1.2.040297.t1(symbB.v1.2.040297.t1)
SPAR: SPRG_05712
 » show all
Taxonomy
Reference
1
  Authors
Nason, A.
  Title
Nitrate reductases.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 587-607.
Reference
2  [PMID:5864033]
  Authors
Paneque A, Del Campo FF, Ramirez JM, Losada M.
  Title
Flavin nucleotide nitrate reductase from spinach.
  Journal
Biochim. Biophys. Acta. 109 (1965) 79-85.
Reference
3  [PMID:11289301]
  Authors
Campbell WH.
  Title
Structure and function of eukaryotic NAD(P)H:nitrate reductase.
  Journal
Cell. Mol. Life. Sci. 58 (2001) 194-204.
Reference
4  [PMID:8534676]
  Authors
Berks BC, Ferguson SJ, Moir JW, Richardson DJ.
  Title
Enzymes and associated electron transport systems that catalyse the respiratory reduction of nitrogen oxides and oxyanions.
  Journal
Biochim. Biophys. Acta. 1232 (1995) 97-173.
Other DBs
ExplorEnz - The Enzyme Database: 1.7.1.2
IUBMB Enzyme Nomenclature: 1.7.1.2
ExPASy - ENZYME nomenclature database: 1.7.1.2
BRENDA, the Enzyme Database: 1.7.1.2
CAS: 9029-27-0

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