KEGG   ENZYME: 1.7.1.2Help
Entry
EC 1.7.1.2                  Enzyme                                 

Name
nitrate reductase [NAD(P)H];
assimilatory nitrate reductase;
assimilatory NAD(P)H-nitrate reductase;
NAD(P)H bispecific nitrate reductase;
nitrate reductase (reduced nicotinamide adenine dinucleotide (phosphate));
nitrate reductase NAD(P)H;
NAD(P)H-nitrate reductase;
nitrate reductase [NAD(P)H2];
NAD(P)H2:nitrate oxidoreductase
Class
Oxidoreductases;
Acting on other nitrogenous compounds as donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
nitrite:NAD(P)+ oxidoreductase
Reaction(IUBMB)
nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+ [RN:R00794 R00796]
Reaction(KEGG)
Substrate
nitrite [CPD:C00088];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
nitrate [CPD:C00244];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
An iron-sulfur molybdenum flavoprotein.
History
EC 1.7.1.2 created 1961 as EC 1.6.6.2, transferred 2002 to EC 1.7.1.2
Pathway
Nitrogen metabolism
Microbial metabolism in diverse environments
Orthology
K10534  
nitrate reductase (NAD(P)H)
Genes
ATH: 
AT1G37130(NIA2) AT1G77760(NIA1)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj0g3v0006719.1(Lj0g3v0006719.1)
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
8274143(NIA)
JCU: 
POP: 
POPTR_0002s08930g(POPTRDRAFT_551506) POPTR_0005s16180g(POPTRDRAFT_818506)
VVI: 
SLY: 
SPEN: 
SOT: 
SIND: 
BVG: 
NNU: 
OSA: 
4330867(OJ1353_F08.4) 4345795(NIA1) 4345798
DOSA: 
Os02t0770800-01(Os02g0770800) Os08t0468100-01(Os08g0468100) Os08t0468700-00(Os08g0468700)
OBR: 
BDI: 
SBI: 
SORBI_04g024300(SORBIDRAFT_04g024300) SORBI_04g034470(SORBIDRAFT_04g034470) SORBI_07g022750(SORBIDRAFT_07g022750)
ZMA: 
100383210(DIA1) 103643134(GRMZM2G076723) 103654219 542278(NAR1S)
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OTA: 
BPG: 
MIS: 
MPP: 
CSL: 
CVR: 
CME: 
CCP: 
NCR: 
NCU05298(nit-3)
NTE: 
NEUTE1DRAFT80350(NEUTE1DRAFT_80350)
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
FPU: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
VDA: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_1092194(AO090012000626) AOR_1_2938154(AO090003001472)
ANG: 
ANI_1_2088064(An07g08910) ANI_1_802074(An08g05610)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
PBN: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
DSQ: 
PCO: 
SHS: 
HIR: 
PSQ: 
ADL: 
GTR: 
LBC: 
MRR: 
CCI: 
CPUT: 
SLA: 
UMA: 
PFP: 
MLR: 
ACAN: 
SMIN: 
v1.2.036677.t1(symbB.v1.2.036677.t1) v1.2.039611.t1(symbB.v1.2.039611.t1) v1.2.040297.t1(symbB.v1.2.040297.t1)
PTI: 
TPS: 
AAF: 
PIF: 
PSOJ: 
SPAR: 
 » show all
Taxonomy
Reference
1
  Authors
Nason, A.
  Title
Nitrate reductases.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 587-607.
Reference
2  [PMID:5864033]
  Authors
Paneque A, Del Campo FF, Ramirez JM, Losada M.
  Title
Flavin nucleotide nitrate reductase from spinach.
  Journal
Biochim. Biophys. Acta. 109 (1965) 79-85.
Reference
3  [PMID:11289301]
  Authors
Campbell WH.
  Title
Structure and function of eukaryotic NAD(P)H:nitrate reductase.
  Journal
Cell. Mol. Life. Sci. 58 (2001) 194-204.
Reference
4  [PMID:8534676]
  Authors
Berks BC, Ferguson SJ, Moir JW, Richardson DJ.
  Title
Enzymes and associated electron transport systems that catalyse the respiratory reduction of nitrogen oxides and oxyanions.
  Journal
Biochim. Biophys. Acta. 1232 (1995) 97-173.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9029-27-0

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