KEGG   ENZYME: 1.8.3.3Help
Entry
EC 1.8.3.3                  Enzyme                                 

Name
glutathione oxidase
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
glutathione:oxygen oxidoreductase
Reaction(IUBMB)
2 glutathione + O2 = glutathione disulfide + H2O2 [RN:R00120]
Reaction(KEGG)
Substrate
glutathione [CPD:C00051];
O2 [CPD:C00007]
Product
glutathione disulfide [CPD:C00127];
H2O2 [CPD:C00027]
Comment
A flavoprotein (FAD). Also acts, more slowly, on L-cysteine and several other thiols.
History
EC 1.8.3.3 created 1989
Pathway
Glutathione metabolism
Reference
1
  Authors
Kusakabe, H., Kuninaka, A. and Yoshino, H.
  Title
Purification and properties of a new enzyme, glutathione oxidase from Penicillium sp.K-6-5.
  Journal
Agric. Biol. Chem. 46 (1982) 2057-2067.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
55467-56-6

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