KEGG   ENZYME: 1.8.4.3Help
Entry
EC 1.8.4.3                  Enzyme                                 

Name
glutathione---CoA-glutathione transhydrogenase;
glutathione-coenzyme A glutathione disulfide transhydrogenase;
glutathione-coenzyme A glutathione disulfide transhydrogenase;
glutathione coenzyme A-glutathione transhydrogenase;
glutathione:coenzyme A-glutathione transhydrogenase;
coenzyme A:oxidized-glutathione oxidoreductase;
coenzyme A:glutathione-disulfide oxidoreductase
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With a disulfide as acceptor
BRITE hierarchy
Sysname
CoA:glutathione-disulfide oxidoreductase
Reaction(IUBMB)
CoA + glutathione disulfide = CoA-glutathione + glutathione [RN:R01111]
Reaction(KEGG)
R01111;
(other) R02409 R04860
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Substrate
CoA [CPD:C00010];
glutathione disulfide [CPD:C00127]
Product
CoA-glutathione [CPD:C00920];
glutathione [CPD:C00051]
History
EC 1.8.4.3 created 1972
Pathway
Cysteine and methionine metabolism
Glutathione metabolism
Reference
1  [PMID:5924646]
  Authors
Chang SH, Wilken DR.
  Title
Participation of the unsymmetrical disulfide of coenzyme A and glutathione in an enzymatic sulfhydryl-disulfide interchange. I. Partial purification and properties of the bovine kidney enzyme.
  Journal
J. Biol. Chem. 241 (1966) 4251-60.
  Organism
Bos taurus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37256-48-7

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