| Entry |
|
|---|
| Name |
glutathione---cystine transhydrogenase;
GSH-cystine transhydrogenase;
NADPH-dependent GSH-cystine transhydrogenase |
|---|
| Class |
Oxidoreductases;
Acting on a sulfur group of donors;
With a disulfide as acceptor
 |
|---|
| Sysname |
glutathione:cystine oxidoreductase |
|---|
| Reaction(IUBMB) |
2 glutathione + cystine = glutathione disulfide + 2 cysteine
[RN:R01109] |
|---|
| Reaction(KEGG) |
R01109 > R01113
 |
|---|
| Substrate |
glutathione [CPD:C00051];
cystine [CPD:C01420] |
|---|
| Product |
glutathione disulfide [CPD:C00127];
cysteine [CPD:C00736] |
|---|
| Pathway |
ec00270 Cysteine and methionine metabolism
ec00480 Glutathione metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:5646485]
Nagai S, Black S.
A thiol-disulfide transhydrogenase from yeast.
J. Biol. Chem. 243 (1968) 1942-7.
Saccharomyces cerevisiae [GN:sce] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.8.4.4
IUBMB Enzyme Nomenclature: 1.8.4.4
ExPASy - ENZYME nomenclature database: 1.8.4.4
BRENDA, the Enzyme Database: 1.8.4.4
CAS: 37256-49-8 |
|---|
