KEGG   ENZYME: 1.8.4.4Help
Entry
EC 1.8.4.4                  Enzyme                                 
Name
glutathione---cystine transhydrogenase;
GSH-cystine transhydrogenase;
NADPH-dependent GSH-cystine transhydrogenase
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With a disulfide as acceptor
BRITE hierarchy
Sysname
glutathione:cystine oxidoreductase
Reaction(IUBMB)
2 glutathione + cystine = glutathione disulfide + 2 cysteine [RN:R01109]
Reaction(KEGG)
Substrate
glutathione [CPD:C00051];
cystine [CPD:C01420]
Product
glutathione disulfide [CPD:C00127];
cysteine [CPD:C00736]
Pathway
Cysteine and methionine metabolism
Glutathione metabolism
Reference
1  [PMID:5646485]
  Authors
Nagai S, Black S.
  Title
A thiol-disulfide transhydrogenase from yeast.
  Journal
J. Biol. Chem. 243 (1968) 1942-7.
  Organism
Saccharomyces cerevisiae [GN:sce]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37256-49-8
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