KEGG   ENZYME: 2.1.1.117Help
Entry
EC 2.1.1.117                Enzyme                                 

Name
(S)-scoulerine 9-O-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + (S)-scoulerine = S-adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine [RN:R03835]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
(S)-scoulerine [CPD:C02106]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
(S)-tetrahydrocolumbamine [CPD:C04118]
Comment
The product of this reaction is a precursor for protoberberine alkaloids in plants
History
EC 2.1.1.117 created 1999
Pathway
Isoquinoline alkaloid biosynthesis
Biosynthesis of secondary metabolites
Orthology
K13397  
(S)-scoulerine 9-O-methyltransferase
Reference
1
  Authors
Muemmler, S., Rueffer, M., Nagakura, N., Zenk, M.H.
  Title
S-Adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase, a highly stereo- and regiospecific enzyme in tetrahydroberberine biosynthesis.
  Journal
Plant Cell Reports 4 (1985) 36-39.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
96380-65-3

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