KEGG   ENZYME: 2.1.1.121Help
Entry
EC 2.1.1.121                Enzyme                                 

Name
6-O-methylnorlaudanosoline 5'-O-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline [RN:R04714]
Reaction(KEGG)
R04714;
(other) R05213
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Substrate
S-adenosyl-L-methionine [CPD:C00019];
6-O-methylnorlaudanosoline [CPD:C05203]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
nororientaline [CPD:C05317]
Comment
Nororientaline is a precursor of the alkaloid papaverine.
History
EC 2.1.1.121 created 1999
Pathway
Isoquinoline alkaloid biosynthesis
Reference
1
  Authors
Rueffer, M., Nagakura, N., Zenk, M.H.
  Title
A highly specific O-methyltransferase for nororientaline synthesis isolated from Argemone platyceras cell cultures.
  Journal
Planta Med. 49 (1983) 196-198.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
89511-99-9

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