| Entry |
|
|---|
| Name |
methylene-fatty-acyl-phospholipid synthase;
unsaturated-phospholipid methyltransferase |
|---|
| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
|---|
| Sysname |
S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase
(methenylating) |
|---|
| Reaction(IUBMB) |
S-adenosyl-L-methionine + phospholipid olefinic fatty acid =
S-adenosyl-L-homocysteine + phospholipid methylene fatty acid
[RN:R03410] |
|---|
| Reaction(KEGG) |
R03410
 |
|---|
| Substrate |
S-adenosyl-L-methionine [CPD:C00019];
phospholipid olefinic fatty acid [CPD:C01229] |
|---|
| Product |
S-adenosyl-L-homocysteine [CPD:C00021];
phospholipid methylene fatty acid [CPD:C04215] |
|---|
| Comment |
The enzyme transfers a methyl group to the 10-position of a
Delta-olefinic acyl chain in phosphatidylglycerol or
phosphatidylinositol or, more slowly, phosphatidylethanolamine;
subsequent proton transfer produces a 10-methylene group (cf. EC
2.1.1.79 cyclopropane-fatty-acyl-phospholipid synthase). |
|---|
| Orthology |
K00550 methylene-fatty-acyl-phospholipid synthase |
|---|
| Genes |
CME: CMP111C
SCE: YJR073C(OPI3)
AGO: AGOS_AFR431C
DHA: DEHA2F17358g
PIC: PICST_56448(OPI3)
CGR: CAGL0F00363g
YLI: YALI0E12441g
SPO: SPBC337.16(cho1)
NCR: NCU04699
MGR: MGG_01295(MG01295.4)
ANI: AN1376.2
AFM: AFUA_1G09050
AOR: AO090005001620
ANG: An08g00560
UMA: UM05725.1
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4313604]
Akamatsu Y, Law JH.
Enzymatic alkylenation of phospholipid fatty acid chains by extracts
of Mycobacterium phlei.
J. Biol. Chem. 245 (1970) 701-8.
Mycobacterium phlei |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.1.16
IUBMB Enzyme Nomenclature: 2.1.1.16
ExPASy - ENZYME nomenclature database: 2.1.1.16
BRENDA, the Enzyme Database: 2.1.1.16
CAS: 37256-90-9 |
|---|
