| Entry |
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|---|
| Name |
23S rRNA (uracil1939-C5)-methyltransferase;
RumA;
RNA uridine methyltransferase A;
YgcA
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
|---|
| Sysname |
S-adenosyl-L-methionine:23S rRNA (uracil1939-C5)-methyltransferase
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + uracil1939 in 23S rRNA = S-adenosyl-L-homocysteine + 5-methyluracil1939 in 23S rRNA
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|---|
| Substrate |
S-adenosyl-L-methionine [CPD: C00019];
uracil1939 in 23S rRNA
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|---|
| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
5-methyluracil1939 in 23S rRNA
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| Comment |
The enzyme specifically methylates uracil1939 at C5 in 23S rRNA [1]. The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues [2].
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| Orthology |
| 23S rRNA (uracil1939-C5)-methyltransferase |
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|---|
| Genes |
ECO: | | ECJ: | | ECD: | | EBW: | | ECOK: | | ECE: | | ECS: | | ECF: | | ETW: | | ELX: | | EOJ: | | EOH: | | ECG: | | EOK: | | ELR: | | ECC: | | ECP: | | ECI: | | ECV: | | ECX: | | ECW: | | ECM: | | ECY: | | ECR: | | ECQ: | | ECK: | | ECT: | | EOC: | | EUM: | | ECZ: | | ELO: | | ELN: | | ELH: | | ESE: | | ESO: | | ESM: | | ESL: | | ECL: | | EBR: | | EBD: | | EKO: | | EKF: | | EAB: | | EDH: | | EDJ: | | EIH: | | ENA: | | ELU: | | EUN: | | ELW: | | ELL: | | ELC: | | ELD: | | ELP: | | EBL: | | EBE: | | ELF: | | ECOA: | | EFE: | | EBT: | | STY: | | STT: | | SEX: | | STM: | | SEO: | | SEV: | | SEY: | | SEM: | | SEJ: | | SEB: | | SEF: | | SETU: | | SPT: | | SEK: | | SPQ: | | SEI: | | SEC: | | SEH: | | SHB: | | SEE: | | SEW: | | SEA: | | SED: | | SEG: | | SET: | | SENJ: | | SES: | | SBG: | | YEN: | | YEP: | | YEY: | | SFL: | | SFX: | | SFV: | | SFE: | | SSN: | | SSJ: | | SBO: | | SBC: | | SDY: | | ECA: | | PCT: | | PCC: | | PWA: | | PEC: | | ETA: | | EPY: | | EPR: | | EAM: | | EAY: | | EBI: | | ERJ: | | PLU: | | PAY: | | SGL: | | ENT: | | ENC: | | ENO: | | ECLO: | | ESC: | | EEC: | | ENL: | | EAS: | | EAE: | | EAR: | | ESA: | | CSK: | | CSZ: | | CTU: | | KPN: | | KPU: | | KPM: | | KPP: | | KPE: | | KPO: | | KVA: | | KOX: | | CKO: | | CRO: | | SMAF: | | SMW: | | PMR: | | EIC: | | ETR: | | ETD: | | ETC: | | DDA: | | DDC: | | DDD: | | DZE: | | XBO: | | XNE: | | PAM: | | PLF: | | PAJ: | | PAQ: | | PVA: | | PAO: | | RAH: | | RAQ: | | RAA: | | PSI: | | MMK: | | ROR: | | EBF: | | HIN: | | HIT: | | HIQ: | | HIF: | | HIL: | | HIU: | | HIE: | | HIZ: | | HDU: | | HAP: | | HPR: | | HSO: | | HSM: | | PMU: | | PMV: | | PUL: | | PMP: | | MSU: | | MHT: | | MHQ: | | MHX: | | APL: | | APJ: | | APA: | | ASU: | | ASI: | | AAP: | | AAT: | | AAO: | | AAN: | | GAN: | | BTO: | | XFA: | | XFT: | | XFM: | | XFN: | | XFF: | | XCC: | | XCB: | | XCA: | | XCV: | | XCP: | | XAC: | | XAX: | | XAO: | | XOO: | | XOM: | | XOP: | | XOR: | | XAL: | | XCI: | | SML: | | SMT: | | BUJ: | | SMZ: | | PSU: | | PSD: | | FAU: | | RHD: | | VCH: | | VCE: | | VCJ: | | VCO: | | VCR: | | VCM: | | VCI: | | VCL: | | VVU: | | VVY: | | VVM: | | VPA: | | VPB: | | VHA: | | VSP: | | VEX: | | VEJ: | | VFU: | | VFI: | | VFM: | | VSA: | | PPR: | | VAN: | | PAE: | | PAU: | | PAP: | | PAG: | | PAF: | | PNC: | | PDK: | | PSG: | | PPU: | | PPF: | | PPG: | | PPW: | | PPT: | | PPB: | | PPI: | | PPUH: | | PPUU: | | PST: | | PSB: | | PSP: | | PFL: | | PFO: | | PFS: | | PFE: | | PFC: | | PPZ: | | PEN: | | PMY: | | PMK: | | PSA: | | PSZ: | | PSR: | | PSC: | | PSJ: | | PSH: | | PBA: | | PFV: | | PDR: | | CJA: | | AVN: | | AVL: | | AVD: | | PAR: | | PCR: | | PRW: | | ACI: | | ACD: | | ABM: | | ABY: | | ABC: | | ABN: | | ABB: | | ABX: | | ABZ: | | ABR: | | ABD: | | ABH: | | ABAD: | | ACC: | | MCT: | | SON: | | SDN: | | SFR: | | SAZ: | | SBL: | | SBM: | | SBN: | | SBP: | | SBT: | | SBS: | | SBB: | | SLO: | | SPC: | | SHP: | | SSE: | | SPL: | | SHE: | | SHM: | | SHN: | | SHW: | | SHL: | | SWD: | | SWP: | | SVO: | | ILO: | | CPS: | | PHA: | | PSM: | | MAQ: | | MHC: | | MAD: | | MBS: | | AMC: | | AMAC: | | AMB: | | AMG: | | AMK: | | AMAA: | | ALT: | | GNI: | | PIN: | | PSY: | | TTU: | | FBL: | | LPN: | | LPU: | | LPF: | | LPP: | | LPC: | | LPA: | | LPE: | | LLO: | | MCA: | | MMT: | | MAH: | | FTU: | | FTF: | | FTW: | | FTR: | | FTT: | | FTG: | | FTL: | | FTH: | | FTA: | | FTS: | | FTI: | | FTM: | | FTN: | | FCF: | | FCN: | | FPH: | | FRT: | | FNA: | | TCX: | | TCY: | | MEJ: | | MEC: | | CYQ: | | NOC: | | NHL: | | NWA: | | ALV: | | TVI: | | TMB: | | AEH: | | HHA: | | TGR: | | TKM: | | TNI: | | HNA: | | HCH: | | CSA: | | HEL: | | ABO: | | ADI: | | KKO: | | MMW: | | MME: | | MPC: | | TOL: | | AHA: | | ASA: | | AVR: | | TAU: | | OCE: | | DNO: | | AFE: | | AFR: | | ACU: | | AFI: | | SAGA: | | VOK: | | GPB: | | NLA: | | CVI: | | LHK: | | PSE: | | RSO: | | RSC: | | RSL: | | RPI: | | RPF: | | REU: | | REH: | | RME: | | CTI: | | CNC: | | BMA: | | BMV: | | BML: | | BMN: | | BPS: | | BPM: | | BPL: | | BPD: | | BPR: | | BPZ: | | BPQ: | | BTE: | | BVI: | | BUR: | | BCN: | | BCH: | | BCM: | | BCJ: | | BAM: | | BAC: | | BMU: | | BMJ: | | BCT: | | BXE: | | BPH: | | BPY: | | BGL: | | BUG: | | BGE: | | BGF: | | BRH: | | BGD: | | BYI: | | BUK: | | BPX: | | PNU: | | PNE: | | BPE: | | BPC: | | BPER: | | BPA: | | BPAR: | | BBR: | | BBM: | | BBH: | | BPT: | | BAV: | | AXY: | | TEQ: | | TEA: | | TEG: | | TAS: | | TAT: | | AKA: | | RFR: | | POL: | | PNA: | | AAV: | | AJS: | | DIA: | | AAA: | | ACK: | | VEI: | | DAC: | | DEL: | | VAP: | | VPE: | | CTT: | | ADN: | | ADK: | | RTA: | | MPT: | | HAR: | | MMS: | | HSE: | | CFU: | | LCH: | | TIN: | | THI: | | RGE: | | NEU: | | NIT: | | NII: | | NMU: | | EBA: | | AZO: | | AZA: | | DAR: | | TMZ: | | DSU: | | TBD: | | MFA: | | MMB: | | MEH: | | MEI: | | MEP: | | APP: | | SLT: | | GCA: | | KCI: | | KCT: | | KBL: | | KBT: | | KDE: | | KGA: | | KON: | | BPRC: | | GSU: | | GSK: | | GME: | | GUR: | | GLO: | | GBM: | | GEO: | | GEM: | | GEB: | | PCA: | | PPD: | | DVG: | | DDN: | | DAS: | | DPI: | | DBA: | | DRT: | | BBA: | | BBAT: | | BEX: | | BMX: | | DPS: | | DAK: | | DPR: | | DSF: | | DOL: | | DAL: | | DAT: | | DTO: | | ADE: | | ACP: | | AFW: | | ANK: | | MXA: | | MFU: | | MSD: | | CCX: | | SUR: | | SCL: | | HOH: | | SAT: | | SFU: | | DBR: | | MLO: | | MCI: | | MOP: | | MAM: | | MES: | | PLA: | | SME: | | SMK: | | SMQ: | | SMX: | | SMI: | | SMEG: | | SMEL: | | SMD: | | RHI: | | SFH: | | SFD: | | ATU: | | ARA: | | AVI: | | AGR: | | RET: | | REC: | | RLE: | | RLT: | | RLG: | | RTR: | | BME: | | BMI: | | BMZ: | | BMG: | | BMW: | | BMF: | | BMB: | | BMC: | | BAA: | | BMS: | | BSI: | | BMT: | | BSV: | | BOV: | | BCS: | | BSK: | | BMR: | | BPP: | | OAN: | | BJA: | | BJU: | | BRA: | | BBT: | | BRS: | | RPA: | | RPB: | | RPC: | | RPD: | | RPE: | | RPT: | | RPX: | | NWI: | | NHA: | | OCA: | | OCG: | | OCO: | | AOL: | | BHE: | | BQR: | | BBK: | | BTR: | | BGR: | | BCD: | | BAUS: | | BVN: | | XAU: | | AZC: | | SNO: | | MEX: | | MEA: | | MDI: | | MCH: | | MRD: | | MET: | | MPO: | | MNO: | | BID: | | MSL: | | HDN: | | HMC: | | RVA: | | PHL: | | MSC: | | CCR: | | CCS: | | CAK: | | CSE: | | PZU: | | BSB: | | AEX: | | SIL: | | SIT: | | RSP: | | RSH: | | RSQ: | | RSK: | | RCP: | | RDE: | | RLI: | | PDE: | | DSH: | | KVU: | | KVL: | | PSF: | | PGA: | | PGL: | | OAT: | | OAR: | | ZMO: | | ZMN: | | ZMM: | | ZMB: | | ZMP: | | NAR: | | NPP: | | SAL: | | SWI: | | SPHM: | | SJP: | | SCH: | | SSY: | | ELI: | | GOX: | | GOH: | | GBE: | | ACR: | | AMV: | | GDI: | | GDJ: | | GXY: | | APT: | | APW: | | APF: | | APU: | | APG: | | APQ: | | APX: | | APZ: | | RRU: | | RRF: | | RCE: | | RPM: | | MAG: | | AZL: | | ALI: | | ABS: | | TMO: | | PBR: | | APB: | | PGV: | | MAI: | | MAN: | | MGM: | | BSU: | | BSR: | | BSL: | | BSH: | | BSY: | | BSS: | | BST: | | BSO: | | BSN: | | BSQ: | | BSUB: | | BSX: | | BLI: | | BLD: | | BAO: | | BAY: | | BAQ: | | BYA: | | BAMP: | | BAML: | | BAZ: | | BQL: | | BXH: | | BQY: | | BAMI: | | BAE: | | BHA: | | BAN: | | BAR: | | BAT: | | BAH: | | BAI: | | BAX: | | BAL: | | BCE: | | BCA: | | BCZ: | | BCR: | | BCB: | | BCU: | | BCG: | | BCQ: | | BCX: | | BNC: | | BCF: | | BCER: | | BCY: | | BTK: | | BTL: | | BTB: | | BTT: | | BTC: | | BTF: | | BTM: | | BTG: | | BTI: | | BTN: | | BTHT: | | BWE: | | BCL: | | BPU: | | BPF: | | BMQ: | | BMD: | | BMH: | | BSE: | | BCO: | | BCK: | | BAG: | | BJS: | | OIH: | | GKA: | | GTN: | | GTH: | | GTE: | | GWC: | | GYC: | | GYA: | | GCT: | | GMC: | | GGH: | | AFL: | | AXL: | | SAU: | | SAV: | | SAW: | | SAH: | | SAJ: | | SAM: | | SAS: | | SAR: | | SAC: | | SAX: | | SAA: | | SAO: | | SAE: | | SAD: | | SUU: | | SUV: | | SUH: | | SUE: | | SUJ: | | SUK: | | SUC: | | SUT: | | SUQ: | | SUZ: | | SUD: | | SUX: | | SUW: | | SUG: | | SUF: | | SAB: | | SUY: | | SAUB: | | SAUM: | | SEP: | | SER: | | SHA: | | SSP: | | SCA: | | SLG: | | SLN: | | SSD: | | SDT: | | SWA: | | LMO: | | LMF: | | LMH: | | LMC: | | LMN: | | LMY: | | LMT: | | LMG: | | LMS: | | LMJ: | | LMQ: | | LML: | | LMP: | | LMW: | | LMX: | | LMZ: | | LMON: | | LMOC: | | LMOS: | | LMOO: | | LMOY: | | LMOT: | | LMOA: | | LMOL: | | LMOG: | | LMOE: | | LMOB: | | LIN: | | LWE: | | LSG: | | LIV: | | LSP: | | HHD: | | ESI: | | EAT: | | EAN: | | MCL: | | BBE: | | PJD: | | GYM: | | PPY: | | PPM: | | PPO: | | PMS: | | PMQ: | | PMW: | | PTA: | | TCO: | | AAD: | | SIV: | | LLA: | | LLK: | | LLT: | | LLS: | | LLC: | | LLM: | | LLR: | | LLN: | | LLI: | | LGR: | | LGV: | | SPY: | | SPZ: | | SPYM: | | SPM: | | SPS: | | SPH: | | SPI: | | SPJ: | | SPK: | | SPF: | | SPA: | | SPB: | | STG: | | SOZ: | | STZ: | | STX: | | SPYA: | | SPN: | | SPD: | | SPR: | | SPW: | | SPX: | | SNE: | | SPV: | | SNM: | | SJJ: | | SPP: | | SNT: | | SNC: | | SNB: | | SNP: | | SNI: | | SNV: | | SNX: | | SND: | | SNU: | | SPNG: | | SPNE: | | SPNU: | | SPNM: | | SPNO: | | SAG: | | SAN: | | SAK: | | SGC: | | SAGS: | | SMU: | | SMC: | | SMJ: | | SMUT: | | STC: | | STL: | | STE: | | STN: | | STU: | | STW: | | SSA: | | SSU: | | SSV: | | SSB: | | SSI: | | SSS: | | SST: | | SSF: | | SSK: | | SSQ: | | SSW: | | SUI: | | SUO: | | SRP: | | SUP: | | SSUS: | | SGO: | | SEQ: | | SEZ: | | SEZO: | | SEU: | | SUB: | | SDS: | | SDG: | | SDA: | | SDC: | | SGA: | | SGG: | | SGT: | | SMB: | | SOR: | | STK: | | STB: | | SCP: | | SCF: | | SSR: | | STF: | | STJ: | | STD: | | SMN: | | SIF: | | SIE: | | LPL: | | LPJ: | | LPT: | | LPS: | | LJO: | | LJF: | | LJH: | | LAC: | | LAI: | | LSA: | | LSL: | | LSI: | | LDB: | | LBU: | | LDE: | | LDL: | | LBR: | | LBK: | | LCA: | | LCB: | | LCZ: | | LCS: | | LCE: | | LCW: | | LGA: | | LRE: | | LRF: | | LRU: | | LHL: | | LHR: | | LFE: | | LFR: | | LRH: | | LRG: | | LRL: | | LRA: | | LCR: | | LAM: | | LAY: | | LBH: | | LBN: | | LKE: | | LRM: | | LSN: | | PPE: | | PCE: | | EFA: | | EFL: | | EFI: | | EFD: | | EFS: | | EFC: | | EFU: | | EFM: | | EHR: | | ENE: | | ECAS: | | MPS: | | MPX: | | THL: | | OOE: | | LME: | | LMM: | | LCI: | | LKI: | | LGS: | | LEC: | | LCN: | | LGE: | | AUR: | | CRN: | | CML: | | WKO: | | CAC: | | CAE: | | CAY: | | CPE: | | CPF: | | CPR: | | CTC: | | CNO: | | CTH: | | CTX: | | CBO: | | CBA: | | CBH: | | CBY: | | CBL: | | CBK: | | CBB: | | CBI: | | CBN: | | CBT: | | CBF: | | CBM: | | CBJ: | | CBE: | | CKL: | | CKR: | | CPY: | | CCE: | | CLJ: | | CSH: | | CSO: | | CCB: | | CLS: | | CLB: | | CCL: | | CAD: | | CSR: | | CSS: | | CSD: | | CDF: | | CDC: | | CDL: | | CDG: | | CST: | | FAA: | | AMT: | | AOE: | | ASF: | | ASB: | | STH: | | SWO: | | SLP: | | DSY: | | DDH: | | DDL: | | DRM: | | DAE: | | DCA: | | DKU: | | DRU: | | PTH: | | DAU: | | TJR: | | DOR: | | DAI: | | DMI: | | DED: | | DEC: | | HMO: | | APR: | | EEL: | | ERE: | | ERT: | | ERA: | | ELM: | | ESR: | | ESU: | | AWO: | | BPB: | | BFI: | | CLE: | | RHO: | | RIX: | | RIM: | | CCT: | | EHA: | | RAL: | | RBR: | | RCH: | | RUM: | | ROB: | | RTO: | | FPR: | | FPA: | | OVA: | | SAY: | | SAP: | | CLO: | | BPRS: | | BPRL: | | TTE: | | TEX: | | THX: | | TPD: | | TIT: | | TMT: | | TBO: | | TWI: | | CHY: | | TEP: | | TAE: | | ADG: | | TPZ: | | CSC: | | ATE: | | COB: | | CHD: | | COW: | | CKI: | | CKN: | | CLC: | | TOC: | | TTM: | | TTO: | | TXY: | | TSH: | | CPO: | | MAS: | | NTH: | | HOR: | | HAS: | | HPK: | | AAR: | | HHL: | | VPR: | | SSG: | | SRI: | | MED: | | MHG: | | AFN: | | AIN: | | ERH: | | EUC: | | MAA: | | MAL: | | MAT: | | MCD: | | MHR: | | MHH: | | MHM: | | MHS: | | MFR: | | MFM: | | MFP: | | MBV: | | MBH: | | MBI: | | MCY: | | CWO: | | PCU: | | PUV: | | WCH: | | SNG: | | TDE: | | TSU: | | TBE: | | TAZ: | | TPI: | | SSM: | | STA: | | STQ: | | SCC: | | SCD: | | SFC: | | LIL: | | LIE: | | LIC: | | LBJ: | | LBL: | | LBI: | | LBF: | | TPX: | | BRM: | | BPO: | | BPJ: | | BPW: | | BIP: | | SBU: | | SGP: | | ABA: | | ACA: | | ACM: | | GMA: | | TSA: | | TRS: | | SUS: | | CTM: | | BTH: | | BFR: | | BFS: | | BFG: | | BVU: | | BHL: | | BSA: | | PGI: | | PGN: | | PGT: | | PAH: | | PDI: | | PPN: | | OSP: | | TFO: | | PMZ: | | PDN: | | PIT: | | PDT: | | AFD: | | ASH: | | RMR: | | RMG: | | CPI: | | NKO: | | PHE: | | PSN: | | SHG: | | SCN: | | HHY: | | CMR: | | BBD: | | EVI: | | CHU: | | SLI: | | RSI: | | FLI: | | EOL: | | FAE: | | MTT: | | GFO: | | FJO: | | FBR: | | FCO: | | FIN: | | COC: | | CCM: | | RBI: | | ZPR: | | CAT: | | RAN: | | RAI: | | RAR: | | RAG: | | RAE: | | FBC: | | WVI: | | KDI: | | LAN: | | ZGA: | | MRS: | | ASL: | | ORH: | | PTQ: | | NDO: | | FBA: | | AAS: | | FSU: | | FSC: | | OTE: | | CAA: | | MIN: | | AMU: | | TAI: | | TLI: | | AMO: | | SYN: | | SYZ: | | SYY: | | SYT: | | SYS: | | SYQ: | | SYC: | | SYF: | | SYP: | | CYA: | | CYB: | | SYNE: | | SYNP: | | TEL: | | MAR: | | CYT: | | CYP: | | CYC: | | CYN: | | CYH: | | CYJ: | | AMR: | | CGC: | | CAN: | | CSN: | | DSL: | | HAO: | | GLP: | | CMP: | | CYU: | | GVI: | | ANA: | | NPU: | | NOS: | | NOP: | | ANB: | | ACY: | | NAZ: | | CSG: | | CALO: | | CALT: | | RIV: | | TER: | | LEP: | | GEI: | | OAC: | | ONI: | | PSEU: | | CEP: | | MIC: | | ARP: | | CTHE: | | PLP: | | SCS: | | CTE: | | CPC: | | CCH: | | CPH: | | CPB: | | CLI: | | PVI: | | PLT: | | PPH: | | PAA: | | CTS: | | IAL: | | DMC: | | DMD: | | TRO: | | STI: | | ATM: | | MHD: | | AAE: | | HYA: | | HHO: | | HYS: | | HTH: | | HTE: | | TAL: | | SUL: | | SAF: | | PMX: | | DTE: | | TMA: | | TPT: | | TTA: | | FPE: | | MPZ: | | DTH: | | DTU: | | TYE: | | DAP: | | FSI: | | TID: | | TOP: | | TTR: | |
» show all
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| Reference |
|
|---|
| Authors |
Agarwalla S, Kealey JT, Santi DV, Stroud RM |
|---|
| Title |
Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli. |
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| Journal |
J. Biol. Chem. 277 (2002) 8835-40. |
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| Reference |
|
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| Authors |
Lee TT, Agarwalla S, Stroud RM |
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| Title |
Crystal structure of RumA, an iron-sulfur cluster containing E. coli ribosomal RNA 5-methyluridine methyltransferase. |
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| Journal |
Structure. 12 (2004) 397-407. |
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| Reference |
|
|---|
| Authors |
Madsen CT, Mengel-Jorgensen J, Kirpekar F, Douthwaite S |
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| Title |
Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry. |
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| Journal |
Nucleic. Acids. Res. 31 (2003) 4738-46. |
|---|
| Reference |
|
|---|
| Authors |
Persaud C, Lu Y, Vila-Sanjurjo A, Campbell JL, Finley J, O'Connor M |
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| Title |
Mutagenesis of the modified bases, m(5)U1939 and psi2504, in Escherichia coli 23S rRNA. |
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| Journal |
Biochem. Biophys. Res. Commun. 392 (2010) 223-7. |
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| Reference |
|
|---|
| Authors |
Agarwalla S, Stroud RM, Gaffney BJ |
|---|
| Title |
Redox reactions of the iron-sulfur cluster in a ribosomal RNA methyltransferase, RumA: optical and EPR studies. |
|---|
| Journal |
J. Biol. Chem. 279 (2004) 34123-9. |
|---|
| Reference |
|
|---|
| Authors |
Lee TT, Agarwalla S, Stroud RM |
|---|
| Title |
A unique RNA Fold in the RumA-RNA-cofactor ternary complex contributes to substrate selectivity and enzymatic function. |
|---|
| Journal |
Cell. 120 (2005) 599-611. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: |
|---|
