KEGG   ENZYME: 2.1.1.211Help
Entry
EC 2.1.1.211                Enzyme                                 

Name
tRNASer (uridine44-2'-O)-methyltransferase;
TRM44
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:tRNASer (uridine44-2'-O)-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + uridine44 in tRNASer = S-adenosyl-L-homocysteine + 2'-O-methyluridine44 in tRNASer
Substrate
S-adenosyl-L-methionine [CPD:C00019];
uridine44 in tRNASer
Product
S-adenosyl-L-homocysteine [CPD:C00021];
2'-O-methyluridine44 in tRNASer
Comment
The 2'-O-methylation of uridine44 contributes to stability of tRNASer(CGA).
History
EC 2.1.1.211 created 2011
Orthology
K15447  tRNASer (uridine44-2'-O)-methyltransferase
Genes
HSA: 152992(TRMT44)
PTR: 100611098(TRMT44)
PPS: 100973988(TRMT44)
GGO: 101153094(TRMT44)
PON: 100450451(TRMT44)
MCC: 722630(TRMT44)
MCF: 102131251(TRMT44)
CSAB: 103246431(TRMT44)
RRO: 104678968(TRMT44)
RBB: 108543229(TRMT44)
CJC: 100396862(TRMT44)
SBQ: 101029381(TRMT44)
MMU: 78890(Trmt44)
RNO: 305443(Trmt44)
CGE: 100766766(Trmt44)
NGI: 103733935(Trmt44)
HGL: 101720763(Trmt44)
CCAN: 109687437(Trmt44)
OCU: 100353152(TRMT44)
TUP: 102501132(TRMT44)
CFA: 488791(TRMT44)
AML: 100468318(TRMT44)
UMR: 103677090(TRMT44)
ORO: 101372938(TRMT44)
FCA: 101088484(TRMT44)
PTG: 102949756(TRMT44)
AJU: 106982704(TRMT44)
BTA: 513470(TRMT44)
BOM: 102283752(TRMT44)
BIU: 109560104(TRMT44)
PHD: 102326493(TRMT44)
CHX: 102179654(TRMT44)
OAS: 101120164(TRMT44)
SSC: 110262048(TRMT44)
CFR: 102515616(TRMT44)
CDK: 105103348(TRMT44)
BACU: 103015637(TRMT44)
LVE: 103075564(TRMT44)
OOR: 101287599(TRMT44)
ECB: 100070415(TRMT44)
EPZ: 103559324(TRMT44)
EAI: 106840063(TRMT44)
MYB: 102247935(TRMT44)
MYD: 102766331(TRMT44)
HAI: 109372915(TRMT44)
RSS: 109434501(TRMT44)
PALE: 102892619(TRMT44)
LAV: 100668355(TRMT44)
TMU: 101358685
MDO: 100020106(TRMT44)
SHR: 100927032(TRMT44)
OAA: 100073411(TRMT44)
GGA: 422871(TRMT44)
MGP: 104910865
CJO: 107313953(TRMT44)
APLA: 101790587(TRMT44)
ACYG: 106033357(TRMT44)
TGU: 100221858(TRMT44)
GFR: 102039824(TRMT44)
FAB: 101810992(TRMT44)
PHI: 102111250(TRMT44)
PMAJ: 107203235(TRMT44)
CCW: 104690762(TRMT44)
FPG: 101919514(TRMT44)
FCH: 102051460(TRMT44)
CLV: 102096839(TRMT44)
EGZ: 104130210(TRMT44)
AAM: 106498655(TRMT44)
ASN: 102379572(TRMT44)
AMJ: 102575928(TRMT44)
PSS: 102446455(TRMT44)
CMY: 102945362(TRMT44)
CPIC: 101933282(TRMT44)
ACS: 100560985(trmt44)
PVT: 110085519(TRMT44)
PBI: 103053536(TRMT44)
GJA: 107119032(TRMT44)
XLA: 398534(trmt44.L)
XTR: 100124986(trmt44)
NPR: 108785821(TRMT44)
DRE: 450066(trmt44)
SANH: 107675143(trmt44) 107704614
SGH: 107566272(trmt44)
IPU: 108267612(trmt44)
AMEX: 103026025(trmt44)
TRU: 101065294(trmt44)
LCO: 104923969(trmt44)
NCC: 104952650(trmt44)
MZE: 101485049(trmt44)
OLA: 101157092(trmt44)
XMA: 102228046(trmt44)
PRET: 103480448(trmt44)
CSEM: 103387082(trmt44)
LCF: 108879993(trmt44)
HCQ: 109516636(trmt44)
BPEC: 110159472(trmt44)
SASA: 106577564(trmt44)
ELS: 105020664(trmt44)
SFM: 108938726(trmt44)
LCM: 102346741(TRMT44)
CMK: 103177397(trmt44)
CIN: 100186778
SPU: 583073
APLC: 110986740
SKO: 102808842
DSI: Dsimw501_GD27029(Dsim_GD27029)
MDE: 101896924
AAG: 5563748
AME: 410286
BIM: 100747647
BTER: 100645882
SOC: 105198388
AEC: 105146588
ACEP: 105622198
PBAR: 105429375
HST: 105181896
CFO: 105252960
LHU: 105667591
PGC: 109853906
TCA: 100142259
DPA: 109539531
NVL: 108561116
BMOR: 101738223
PMAC: 106720339
PRAP: 110996860
API: 100164460
DNX: 107173631
ZNE: 110832228
FCD: 110846407
CEL: CELE_C23G10.7(C23G10.7)
CBR: CBG24265
BMY: Bm1_13355
TSP: Tsp_06632
CRG: 105322474
OBI: 106870356
SHX: MS3_09487
HMG: 100203277
AQU: 100639695
SCE: YPL030W(TRM44)
ERC: Ecym_2530
KMX: KLMA_60386(TRM44)
NCS: NCAS_0C02480(NCAS0C02480)
NDI: NDAI_0E03180(NDAI0E03180)
TPF: TPHA_0C01790(TPHA0C01790)
TBL: TBLA_0D02710(TBLA0D02710)
TDL: TDEL_0B01550(TDEL0B01550)
KAF: KAFR_0H01540(KAFR0H01540)
CAL: CAALFM_C104530CA(CaO19.6847)
CAUR: QG37_01850
SLB: AWJ20_2999(TRM44)
NCR: NCU01980
NTE: NEUTE1DRAFT89496(NEUTE1DRAFT_89496)
MGR: MGG_15289
MAW: MAC_05338
MAJ: MAA_03731
CMT: CCM_06439
MBE: MBM_09561
ANI: AN8721.2
ANG: ANI_1_970104(An12g07960)
ABE: ARB_07659
TVE: TRV_05158
PTE: PTT_08143
CNE: CNG03590
CNB: CNBG1180
ABP: AGABI1DRAFT44243(AGABI1DRAFT_44243)
ABV: AGABI2DRAFT209065(AGABI2DRAFT_209065)
MGL: MGL_3438
DFA: DFA_09004
 » show all
Taxonomy
Reference
1  [PMID:18025252]
  Authors
Kotelawala L, Grayhack EJ, Phizicky EM
  Title
Identification of yeast tRNA Um(44) 2'-O-methyltransferase (Trm44) and demonstration of a Trm44 role in sustaining levels of specific tRNA(Ser) species.
  Journal
RNA. 14 (2008) 158-69.
  Sequence
[sce:YPL030W]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.211
IUBMB Enzyme Nomenclature: 2.1.1.211
ExPASy - ENZYME nomenclature database: 2.1.1.211
BRENDA, the Enzyme Database: 2.1.1.211

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