KEGG   ENZYME: 2.1.1.237Help
Entry
EC 2.1.1.237                Enzyme                                 

Name
mycinamicin III 3''-O-methyltransferase;
MycF
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:mycinamicin III 3''-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + mycinamicin III = S-adenosyl-L-homocysteine + mycinamicin IV [RN:R09823]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
mycinamicin III [CPD:C15681]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
mycinamicin IV [CPD:C18846]
Comment
The enzyme is involved in the biosynthesis of mycinamicin macrolide antibiotics.
History
EC 2.1.1.237 created 2011
Reference
1  [PMID:19415708]
  Authors
Li S, Anzai Y, Kinoshita K, Kato F, Sherman DH
  Title
Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics.
  Journal
Chembiochem. 10 (2009) 1297-301.
  Organism
Micromonospora griseorubida
  Sequence
[up:Q49492]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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