KEGG   ENZYME: 2.1.1.243Help
Entry
EC 2.1.1.243                Enzyme                                 

Name
2-ketoarginine methyltransferase;
mrsA (gene name)
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:5-carbamimidamido-2-oxopentanoate S-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 5-guanidino-2-oxopentanoate = S-adenosyl-L-homocysteine + 5-guanidino-3-methyl-2-oxopentanoate [RN:R09939]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
5-guanidino-2-oxopentanoate [CPD:C03771]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
5-guanidino-3-methyl-2-oxopentanoate [CPD:C20234]
Comment
The enzyme is involved in production of the rare amino acid 3-methylarginine, which is used by the epiphytic bacterium Pseudomonas syringae pv. syringae as an antibiotic against the related pathogenic species Pseudomonas syringae pv. glycinea.
History
EC 2.1.1.243 created 2012
Orthology
K16215  
2-ketoarginine methyltransferase
Genes
PSB: 
BPS: 
BPM: 
BPL: 
BPD: 
BPR: 
BPZ: 
BGD: 
AAV: 
SBH: 
Taxonomy
Reference
1  [PMID:20190091]
  Authors
Braun SD, Hofmann J, Wensing A, Ullrich MS, Weingart H, Volksch B, Spiteller D
  Title
Identification of the biosynthetic gene cluster for 3-methylarginine, a toxin produced by Pseudomonas syringae pv. syringae 22d/93.
  Journal
Appl. Environ. Microbiol. 76 (2010) 2500-8.
  Organism
Pseudomonas syringae [GN:psb]
  Sequence
[psb:Psyr_0118]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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