KEGG   ENZYME: 2.1.1.259Help
Entry
EC 2.1.1.259                Enzyme                                 

Name
[fructose-bisphosphate aldolase]-lysine N-methyltransferase;
rubisco methyltransferase;
ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase;
ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase;
S-adenosyl-L-methionine:[3-phospho-D-glycerate-carboxy-lyase (dimerizing)]-lysine 6-N-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:[fructose-bisphosphate aldolase]-lysine N6-methyltransferase
Reaction(IUBMB)
3 S-adenosyl-L-methionine + [fructose-bisphosphate aldolase]-L-lysine = 3 S-adenosyl-L-homocysteine + [fructose-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine
Substrate
S-adenosyl-L-methionine [CPD:C00019];
[fructose-bisphosphate aldolase]-L-lysine [CPD:C21364]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
[fructose-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine [CPD:C21365]
Comment
The enzyme methylates a conserved lysine in the C-terminal part of higher plant fructose-bisphosphate aldolase (EC 4.1.2.13). The enzyme from pea (Pisum sativum) also methylates Lys-14 in the large subunits of hexadecameric higher plant ribulose-bisphosphate-carboxylase (EC 4.1.1.39) [2], but that from Arabidopsis thaliana does not.
History
EC 2.1.1.259 created 2012
Orthology
K00592  
[ribulose-bisphosphate carboxylase]/[fructose-bisphosphate aldolase]-lysine N-methyltransferase
Genes
ATH: 
AT1G14030(LSMT-L)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
BOE: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
GHI: 
EGR: 
GMX: 
PVU: 
VRA: 
VAR: 
CCAJ: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj4g3v0684250.1(Lj4g3v0684250.1) Lj4g3v0684250.2(Lj4g3v0684250.2)
LANG: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
ZJU: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
VVI: 
SLY: 
SPEN: 
SOT: 
CANN: 
NTA: 
INI: 
SIND: 
BVG: 
NNU: 
OSA: 
9266797(OJ1294_G06.18)
DOSA: 
Os09t0411650-01(Os09g0411650)
OBR: 
BDI: 
ATS: 
SBI: 
ZMA: 
SITA: 
PDA: 
EGU: 
MUS: 
DCT: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
MNG: 
OLU: 
OTA: 
BPG: 
MIS: 
MPP: 
CSL: 
CVR: 
GSL: 
CCP: 
NGD: 
PIF: 
PSOJ: 
SPAR: 
EHX: 
GTT: 
 » show all
Taxonomy
Reference
1  [PMID:17635932]
  Authors
Magnani R, Nayak NR, Mazarei M, Dirk LM, Houtz RL
  Title
Polypeptide substrate specificity of PsLSMT. A set domain protein methyltransferase.
  Journal
J. Biol. Chem. 282 (2007) 27857-64.
Reference
2  [PMID:22547063]
  Authors
Mininno M, Brugiere S, Pautre V, Gilgen A, Ma S, Ferro M, Tardif M, Alban C, Ravanel S
  Title
Characterization of chloroplastic fructose 1,6-bisphosphate aldolases as lysine-methylated proteins in plants.
  Journal
J. Biol. Chem. 287 (2012) 21034-44.
  Sequence
[ath:AT1G14030] [ag:AAA69903]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

DBGET integrated database retrieval system