KEGG   ENZYME: 2.1.1.259Help
Entry
EC 2.1.1.259                Enzyme                                 

Name
[fructose-bisphosphate aldolase]-lysine N-methyltransferase;
rubisco methyltransferase;
ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase;
ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase;
S-adenosyl-L-methionine:[3-phospho-D-glycerate-carboxy-lyase (dimerizing)]-lysine 6-N-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:[fructose-bisphosphate aldolase]-lysine N6-methyltransferase
Reaction(IUBMB)
3 S-adenosyl-L-methionine + [fructose-bisphosphate aldolase]-L-lysine = 3 S-adenosyl-L-homocysteine + [fructose-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine
Substrate
S-adenosyl-L-methionine [CPD:C00019];
[fructose-bisphosphate aldolase]-L-lysine [CPD:C21364]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
[fructose-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine [CPD:C21365]
Comment
The enzyme methylates a conserved lysine in the C-terminal part of higher plant fructose-bisphosphate aldolase (EC 4.1.2.13). The enzyme from pea (Pisum sativum) also methylates Lys-14 in the large subunits of hexadecameric higher plant ribulose-bisphosphate-carboxylase (EC 4.1.1.39) [2], but that from Arabidopsis thaliana does not.
History
EC 2.1.1.259 created 2012
Orthology
K00592  [ribulose-bisphosphate carboxylase]/[fructose-bisphosphate aldolase]-lysine N-methyltransferase
Genes
ATH: AT1G14030(LSMT-L)
ALY: ARALYDRAFT_471564
CSAT: 104740061 104755697 104772851
EUS: EUTSA_v10007614mg
BRP: 103843008
BNA: 106369122 106415812
BOE: 106307554
THJ: 104801808
CPAP: 110814551
CIT: 102629962
TCC: 18610345
GRA: 105794210
DZI: 111318315
VRA: 106766684
VAR: 108345304
CCAJ: 109790121
CAM: 101490590
ADU: 107481199
AIP: 107631855
LJA: Lj4g3v0684250.1(Lj4g3v0684250.1) Lj4g3v0684250.2(Lj4g3v0684250.2)
FVE: 101298121
PPER: 18793936
PMUM: 103321538
PAVI: 110751405
MDM: 103425473
PXB: 103947201
ZJU: 107428930
CSV: 101205332
CMO: 103485765
MCHA: 111023237
RCU: 8281847
JCU: 105630482
VVI: 100243771
SLY: 101259632
NTA: 107778201(RBCMT) 107809813
NSY: 104226426
NTO: 104089653
INI: 109161120
SIND: 105159997
OEU: 111398907
HAN: 110911425
BVG: 104897864
SOE: 110785063
NNU: 104598072
OSA: 9266797
DOSA: Os09t0411650-01(Os09g0411650)
OBR: 102703061
BDI: 100823096
ATS: 109773851(LOC109773851)
SBI: 8063304
ZMA: 100382373
SITA: 101771156
PDA: 103714847
EGU: 105058571
DCT: 110107875
AOF: 109826056
ATR: 18422052
CRE: CHLREDRAFT_193086(RMT1)
VCN: VOLCADRAFT_109735(VRMT1)
MNG: MNEG_7683
SPAR: SPRG_03390
 » show all
Taxonomy
Reference
1  [PMID:17635932]
  Authors
Magnani R, Nayak NR, Mazarei M, Dirk LM, Houtz RL
  Title
Polypeptide substrate specificity of PsLSMT. A set domain protein methyltransferase.
  Journal
J. Biol. Chem. 282 (2007) 27857-64.
Reference
2  [PMID:22547063]
  Authors
Mininno M, Brugiere S, Pautre V, Gilgen A, Ma S, Ferro M, Tardif M, Alban C, Ravanel S
  Title
Characterization of chloroplastic fructose 1,6-bisphosphate aldolases as lysine-methylated proteins in plants.
  Journal
J. Biol. Chem. 287 (2012) 21034-44.
  Sequence
[ath:AT1G14030] [ag:AAA69903]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.259
IUBMB Enzyme Nomenclature: 2.1.1.259
ExPASy - ENZYME nomenclature database: 2.1.1.259
BRENDA, the Enzyme Database: 2.1.1.259

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