KEGG   ENZYME: 2.1.1.273Help
Entry
EC 2.1.1.273                Enzyme                                 

Name
benzoate O-methyltransferase;
BAMT;
S-adenosyl-L-methionine:benzoic acid carboxyl methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:benzoate O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + benzoate = S-adenosyl-L-homocysteine + methyl benzoate [RN:R10447]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
benzoate [CPD:C00180]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
methyl benzoate [CPD:C20645]
Comment
While the enzyme from the plant Zea mays is specific for benzoate [6], the enzymes from Arabidopsis species and Clarkia breweri also catalyse the reaction of EC 2.1.1.274, salicylate 1-O-methyltransferase [1,5]. In snapdragon (Antirrhinum majus) two isoforms are found, one specific for benzoate [2,3] and one that is also active towards salicylate [4]. The volatile product is an important scent compound in some flowering species [2].
History
EC 2.1.1.273 created 2013
Orthology
K21482  benzoate O-methyltransferase
K21484  benzoate/salicylate 1-O-methyltransferase
Genes
ATH: AT3G11480(BSMT1) AT5G04370(NAMT1) AT5G04380 AT5G66430
ALY: ARALYDRAFT_487217 ARALYDRAFT_897350
CRB: 17893670
CSAT: 104708682 104727399 104734448 104745350 104745353 104745842 104746543 104762932 104764901 104766009 104768626 104773442 109130817
EUS: EUTSA_v10013754mg EUTSA_v10022292mg
BRP: 103837152 103847295 103847297 103847298 103847299 103855566 103859391 103870342 103870344
BNA: 106345178 106345495 106346584 106353051 106362614 106364005 106366900 106370700 106372697 106372698 106383478 106416291 106416341 106423490 106436478 106436480 106436482 106440340 106442990
BOE: 106302931 106313641 106316499 106318326 106318327 106329214 106332554
THJ: 104819197 104819198 104820147
CIT: 102624846 102625129 102625698
TCC: 18589945
GRA: 105775995
POP: 7487202
JRE: 108983849
SPEN: 107015380
CANN: 107857182
NSY: 104246528
NTO: 104120721
NNU: 104595931
OBR: 102706569
SBI: 110434364
ZMA: 100282829 100500709(OMT8)
SITA: 101766563
 » show all
Taxonomy
Reference
1  [PMID:10375393]
  Authors
Ross JR, Nam KH, D'Auria JC, Pichersky E
  Title
S-Adenosyl-L-methionine:salicylic acid carboxyl methyltransferase, an enzyme involved in floral scent production and plant defense, represents a new class of  plant methyltransferases.
  Journal
Arch. Biochem. Biophys. 367 (1999) 9-16.
Reference
2  [PMID:10852939]
  Authors
Dudareva N, Murfitt LM, Mann CJ, Gorenstein N, Kolosova N, Kish CM, Bonham C, Wood K
  Title
Developmental regulation of methyl benzoate biosynthesis and emission in snapdragon flowers.
  Journal
Plant. Cell. 12 (2000) 949-61.
  Sequence
Reference
3  [PMID:11051108]
  Authors
Murfitt LM, Kolosova N, Mann CJ, Dudareva N
  Title
Purification and characterization of S-adenosyl-L-methionine:benzoic acid carboxyl methyltransferase, the enzyme responsible for biosynthesis of the volatile ester methyl benzoate in flowers of Antirrhinum majus.
  Journal
Arch. Biochem. Biophys. 382 (2000) 145-51.
Reference
4  [PMID:12361714]
  Authors
Negre F, Kolosova N, Knoll J, Kish CM, Dudareva N
  Title
Novel S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase, an enzyme responsible for biosynthesis of methyl salicylate and methyl benzoate, is  not involved in floral scent production in snapdragon flowers.
  Journal
Arch. Biochem. Biophys. 406 (2002) 261-70.
Reference
5  [PMID:14617060]
  Authors
Chen F, D'Auria JC, Tholl D, Ross JR, Gershenzon J, Noel JP, Pichersky E
  Title
An Arabidopsis thaliana gene for methylsalicylate biosynthesis, identified by a biochemical genomics approach, has a role in defense.
  Journal
Plant. J. 36 (2003) 577-88.
  Sequence
[ath:AT3G11480]
Reference
6  [PMID:20519632]
  Authors
Kollner TG, Lenk C, Zhao N, Seidl-Adams I, Gershenzon J, Chen F, Degenhardt J
  Title
Herbivore-induced SABATH methyltransferases of maize that methylate anthranilic acid using s-adenosyl-L-methionine.
  Journal
Plant. Physiol. 153 (2010) 1795-807.
  Sequence
[zma:100500709]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.273
IUBMB Enzyme Nomenclature: 2.1.1.273
ExPASy - ENZYME nomenclature database: 2.1.1.273
BRENDA, the Enzyme Database: 2.1.1.273

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