KEGG   ENZYME: 2.1.1.274Help
Entry
EC 2.1.1.274                Enzyme                                 

Name
salicylate 1-O-methyltransferase;
SAMT;
S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase;
salicylate carboxymethyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:salicylate 1-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + salicylate = S-adenosyl-L-homocysteine + methyl salicylate [RN:R10448]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
salicylate [CPD:C00805]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
methyl salicylate [CPD:C12305]
Comment
The enzyme, which is found in flowering plants, also has the activity of EC 2.1.1.273, benzoate O-methyltransferase.
History
EC 2.1.1.274 created 2013
Reference
1  [PMID:10375393]
  Authors
Ross JR, Nam KH, D'Auria JC, Pichersky E
  Title
S-Adenosyl-L-methionine:salicylic acid carboxyl methyltransferase, an enzyme involved in floral scent production and plant defense, represents a new class of  plant methyltransferases.
  Journal
Arch. Biochem. Biophys. 367 (1999) 9-16.
  Sequence
Reference
2  [PMID:12361714]
  Authors
Negre F, Kolosova N, Knoll J, Kish CM, Dudareva N
  Title
Novel S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase, an enzyme responsible for biosynthesis of methyl salicylate and methyl benzoate, is  not involved in floral scent production in snapdragon flowers.
  Journal
Arch. Biochem. Biophys. 406 (2002) 261-70.
Reference
3  [PMID:14617060]
  Authors
Chen F, D'Auria JC, Tholl D, Ross JR, Gershenzon J, Noel JP, Pichersky E
  Title
An Arabidopsis thaliana gene for methylsalicylate biosynthesis, identified by a biochemical genomics approach, has a role in defense.
  Journal
Plant. J. 36 (2003) 577-88.
Reference
4  [PMID:12897246]
  Authors
Zubieta C, Ross JR, Koscheski P, Yang Y, Pichersky E, Noel JP
  Title
Structural basis for substrate recognition in the salicylic acid carboxyl methyltransferase family.
  Journal
Plant. Cell. 15 (2003) 1704-16.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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