KEGG   ENZYME: 2.1.1.278Help
Entry
EC 2.1.1.278                Enzyme                                 

Name
indole-3-acetate O-methyltransferase;
IAA carboxylmethyltransferase;
IAMT
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:(indol-3-yl)acetate O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + (indol-3-yl)acetate = S-adenosyl-L-homocysteine + methyl (indol-3-yl)acetate [RN:R10452]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
(indol-3-yl)acetate [CPD:C00954]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
methyl (indol-3-yl)acetate [CPD:C20635]
Comment
Binds Mg2+. The enzyme is found in plants and is important for regulation of the plant hormone (indol-3-yl)acetate. The product, methyl (indol-3-yl)acetate is inactive as hormone [2].
History
EC 2.1.1.278 created 2013
Orthology
K18848  
indole-3-acetate O-methyltransferase
Genes
ATH: 
AT5G55250(IAMT1)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj2g3v3222870.1(Lj2g3v3222870.1) Lj6g3v0819010.1(Lj6g3v0819010.1)
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
VVI: 
SLY: 
SPEN: 
SOT: 
SIND: 
BVG: 
NNU: 
OSA: 
107276275 4337315(IAMT1) 4340899(P0421H01.8)
DOSA: 
Os04t0665200-01(Os04g0665200) Os06t0322400-00(Os06g0322400) Os06t0323100-01(Os06g0323100)
OBR: 
PDA: 
EGU: 
MUS: 
ATR: 
 » show all
Taxonomy
Reference
1  [PMID:12897246]
  Authors
Zubieta C, Ross JR, Koscheski P, Yang Y, Pichersky E, Noel JP
  Title
Structural basis for substrate recognition in the salicylic acid carboxyl methyltransferase family.
  Journal
Plant. Cell. 15 (2003) 1704-16.
  Sequence
[ath:AT5G55250]
Reference
2  [PMID:17926040]
  Authors
Li L, Hou X, Tsuge T, Ding M, Aoyama T, Oka A, Gu H, Zhao Y, Qu LJ
  Title
The possible action mechanisms of indole-3-acetic acid methyl ester in Arabidopsis.
  Journal
Plant. Cell. Rep. 27 (2008) 575-84.
  Sequence
[ath:AT5G55250]
Reference
3  [PMID:18162595]
  Authors
Zhao N, Ferrer JL, Ross J, Guan J, Yang Y, Pichersky E, Noel JP, Chen F
  Title
Structural, biochemical, and phylogenetic analyses suggest that indole-3-acetic acid methyltransferase is an evolutionarily ancient member of the SABATH family.
  Journal
Plant. Physiol. 146 (2008) 455-67.
  Sequence
[osa:4337315]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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