KEGG   ENZYME: 2.1.1.295Help
Entry
EC 2.1.1.295                Enzyme                                 

Name
2-methyl-6-phytyl-1,4-hydroquinone methyltransferase;
VTE3 (gene name);
2-methyl-6-solanyl-1,4-hydroquinone methyltransferase;
MPBQ/MSBQ methyltransferase;
MPBQ/MSBQ MT
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:2-methyl-6-phytyl-1,4-benzoquinol C-3-methyltransferase
Reaction(IUBMB)
(1) S-adenosyl-L-methionine + 2-methyl-6-phytylbenzene-1,4-diol = S-adenosyl-L-homocysteine + 2,3-dimethyl-6-phytylbenzene-1,4-diol [RN:R07501];
(2) S-adenosyl-L-methionine + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol = S-adenosyl-L-homocysteine + plastoquinol [RN:R10709];
(3) S-adenosyl-L-methionine + 6-geranylgeranyl-2-methylbenzene-1,4-diol = S-adenosyl-L-homocysteine + 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol [RN:R10710]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
2-methyl-6-phytylbenzene-1,4-diol [CPD:C15882];
2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol [CPD:C17570];
6-geranylgeranyl-2-methylbenzene-1,4-diol [CPD:C20737]
Product
plastoquinol [CPD:C16695]
Comment
Involved in the biosynthesis of plastoquinol, as well as vitamin E (tocopherols and tocotrienols).
History
EC 2.1.1.295 created 2014
Pathway
Ubiquinone and other terpenoid-quinone biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K12502  
MPBQ/MSBQ methyltransferase
K18534  
MPBQ/MSBQ methyltransferase
Genes
ATH: 
AT3G63410(APG1)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
AIP: 
107624907(mpbqmt)
LJA: 
Lj5g3v1014830.1(Lj5g3v1014830.1) Lj5g3v1208090.1(Lj5g3v1208090.1)
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
POPTR_0002s04790g(POPTRDRAFT_643239) POPTR_0005s23740g(POPTRDRAFT_559613) POPTR_0008s15920g(POPTRDRAFT_832825)
VVI: 
SLY: 
SPEN: 
SOT: 
SIND: 
BVG: 
NNU: 
OSA: 
4352791(E37)
DOSA: 
Os07t0179300-00(Os07g0179300) Os12t0615400-01(Os12g0615400)
OBR: 
BDI: 
SBI: 
SORBI_08g021580(SORBIDRAFT_08g021580) SORBI_08g021610(SORBIDRAFT_08g021610)
ZMA: 
100284931(pco114350(339))
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OTA: 
BPG: 
MIS: 
MPP: 
CSL: 
CVR: 
APRO: 
CME: 
GSL: 
CCP: 
PTI: 
TPS: 
AAF: 
EHX: 
GTT: 
SCX: 
SYN: 
SYZ: 
SYY: 
SYNGTS_1914(sll0418)
SYT: 
SYNGTI_1913(sll0418)
SYS: 
SYNPCCN_1912(sll0418)
SYQ: 
SYNPCCP_1912(sll0418)
SYJ: 
SYW: 
SYC: 
SYF: 
SYD: 
SYE: 
SYG: 
SYR: 
SYX: 
SYP: 
CYA: 
CYB: 
SYNK: 
SYNR: 
SYND: 
SYU: 
SYH: 
TEL: 
THN: 
CGC: 
DSL: 
CMP: 
LEP: 
LEN: 
LET: 
PSEU: 
PMA: 
PMM: 
PMT: 
PMN: 
PMI: 
PMB: 
PMC: 
PMF: 
PMG: 
PMH: 
PMJ: 
PME: 
PRC: 
PRM: 
AMR: 
MAR: 
MPK: 
CAN: 
CSN: 
HAO: 
CYU: 
GLP: 
GEN: 
GEE: 
CYT: 
CYC: 
TER: 
MIC: 
ARP: 
OAC: 
ONI: 
ANA: 
NON: 
AVA: 
CALO: 
CALT: 
CALH: 
RIV: 
FIS: 
PLP: 
SCS: 
CEO: 
NIO: 
 » show all
Taxonomy
Reference
1  [PMID:11821038]
  Authors
Shintani DK, Cheng Z, DellaPenna D
  Title
The role of 2-methyl-6-phytylbenzoquinone methyltransferase in determining tocopherol composition in Synechocystis sp. PCC6803.
  Journal
FEBS. Lett. 511 (2002) 1-5.
  Sequence
[syn:sll0418]
Reference
2  [PMID:14508009]
  Authors
Cheng Z, Sattler S, Maeda H, Sakuragi Y, Bryant DA, DellaPenna D.
  Title
Highly divergent methyltransferases catalyze a conserved reaction in tocopherol and plastoquinone synthesis in cyanobacteria and photosynthetic eukaryotes.
  Journal
Plant. Cell. 15 (2003) 2343-56.
  Sequence
Reference
3  [PMID:14630966]
  Authors
Van Eenennaam AL, Lincoln K, Durrett TP, Valentin HE, Shewmaker CK, Thorne GM, Jiang J, Baszis SR, Levering CK, Aasen ED, Hao M, Stein JC, Norris SR, Last RL
  Title
Engineering vitamin E content: from Arabidopsis mutant to soy oil.
  Journal
Plant. Cell. 15 (2003) 3007-19.
  Sequence
[ath:AT3G63410] [ana:all2121]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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