KEGG   ENZYME: 2.1.1.3Help
Entry
EC 2.1.1.3                  Enzyme                                 

Name
thetin---homocysteine S-methyltransferase;
dimethylthetin-homocysteine methyltransferase;
thetin-homocysteine methylpherase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
dimethylsulfonioacetate:L-homocysteine S-methyltransferase
Reaction(IUBMB)
dimethylsulfonioacetate + L-homocysteine = S-methylthioglycolate + L-methionine [RN:R04153]
Reaction(KEGG)
Substrate
dimethylsulfonioacetate [CPD:C03392];
L-homocysteine [CPD:C00155]
Product
S-methylthioglycolate [CPD:C03173];
L-methionine [CPD:C00073]
History
EC 2.1.1.3 created 1961
Reference
1  [PMID:14456704]
  Authors
KLEE WA, RICHARDS HH, CANTONI GL.
  Title
The synthesis of methionine by enzymic transmethylation. VII. Existence of two separate homocysteine methylpherases on mammalian liver.
  Journal
Biochim. Biophys. Acta. 54 (1961) 157-64.
Reference
2  [PMID:13315256]
  Authors
MAW GA.
  Title
Thetin-homocysteine transmethylase; a preliminary manometric study of the enzyme from rat liver.
  Journal
Biochem. J. 63 (1956) 116-24.
Reference
3  [PMID:13584318]
  Authors
MAW GA.
  Title
Thetin-homocysteine transmethylase; some further characteristics of the enzyme from rat liver.
  Journal
Biochem. J. 70 (1958) 168-73.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9029-76-9

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