KEGG   ENZYME: 2.1.1.42Help
Entry
EC 2.1.1.42                 Enzyme                                 

Name
flavone 3'-O-methyltransferase;
o-dihydric phenol methyltransferase;
luteolin methyltransferase;
luteolin 3'-O-methyltransferase;
o-diphenol m-O-methyltransferase;
o-dihydric phenol meta-O-methyltransferase;
S-adenosylmethionine:flavone/flavonol 3'-O-methyltransferase;
quercetin 3'-O-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:3'-hydroxyflavone 3'-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 3'-hydroxyflavone = S-adenosyl-L-homocysteine + 3'-methoxyflavone [RN:R03587]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
3'-hydroxyflavone
Product
S-adenosyl-L-homocysteine [CPD:C00021];
3'-methoxyflavone
Comment
The enzyme prefers flavones with vicinal 3',4'-dihydroxyl groups.
History
EC 2.1.1.42 created 1976, modified 2011
Reference
1  [PMID:5026305]
  Authors
Ebel J, Hahlbrock K, Grisebach H.
  Title
Purification and properties of an o-dihydricphenol meta-O-methyltransferase from cell suspension cultures of parsley and its relation to flavonoid biosynthesis.
  Journal
Biochim. Biophys. Acta. 268 (1972) 313-26.
Reference
2  [PMID:10700397]
  Authors
Muzac I, Wang J, Anzellotti D, Zhang H, Ibrahim RK
  Title
Functional expression of an Arabidopsis cDNA clone encoding a flavonol 3'-O-methyltransferase and characterization of the gene product.
  Journal
Arch. Biochem. Biophys. 375 (2000) 385-8.
  Sequence
[up:Q9FK25]
Reference
3  [PMID:18099]
  Authors
Poulton JE, Hahlbrock K, Grisebach H
  Title
O-Methylation of flavonoid substrates by a partially purified enzyme from soybean cell suspension cultures.
  Journal
Arch. Biochem. Biophys. 180 (1977) 543-9.
Reference
4  [PMID:16777424]
  Authors
Kim BG, Lee HJ, Park Y, Lim Y, Ahn JH
  Title
Characterization of an O-methyltransferase from soybean.
  Journal
Plant. Physiol. Biochem. 44 (2006) 236-41.
Reference
5  [PMID:17943312]
  Authors
Lee YJ, Kim BG, Chong Y, Lim Y, Ahn JH
  Title
Cation dependent O-methyltransferases from rice.
  Journal
Planta. 227 (2008) 641-7.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37205-55-3

DBGET integrated database retrieval system