KEGG   ENZYME: 2.1.1.54Help
Entry
EC 2.1.1.54                 Enzyme                                 

Name
deoxycytidylate C-methyltransferase;
deoxycytidylate methyltransferase;
dCMP methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
5,10-methylenetetrahydrofolate:dCMP C-methyltransferase
Reaction(IUBMB)
5,10-methylenetetrahydrofolate + dCMP = dihydrofolate + deoxy-5-methylcytidylate [RN:R01670]
Reaction(KEGG)
Substrate
5,10-methylenetetrahydrofolate [CPD:C00143];
dCMP [CPD:C00239]
Product
dihydrofolate [CPD:C00415];
deoxy-5-methylcytidylate [CPD:C03495]
Comment
dCMP is methylated by formaldehyde in the presence of tetrahydrofolate. CMP, dCTP and CTP can act as acceptors, but more slowly.
History
EC 2.1.1.54 created 1978
Reference
1  [PMID:980110]
  Authors
Kuo TT, Tu J.
  Title
Enzymatic synthesis of deoxy-5-methyl-cytidylic acid replacing deoxycytidylic acid in Xanthomonas oryzae phage Xp12DNA.
  Journal
Nature. 263 (1976) 615.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
61970-01-2

DBGET integrated database retrieval system