KEGG   ENZYME: 2.1.1.68Help
Entry
EC 2.1.1.68                 Enzyme                                 

Name
caffeate O-methyltransferase;
caffeate methyltransferase;
caffeate 3-O-methyltransferase;
S-adenosyl-L-methionine:caffeic acid-O-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate [RN:R03366]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
3,4-dihydroxy-trans-cinnamate [CPD:C01197]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
3-methoxy-4-hydroxy-trans-cinnamate [CPD:C01494]
Comment
3,4-Dihydroxybenzaldehyde and catechol can act as acceptors, but more slowly.
History
EC 2.1.1.68 created 1984
Pathway
Phenylpropanoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K13066  
caffeic acid 3-O-methyltransferase
Genes
ATH: 
AT5G54160(OMT1)
ALY: 
CRB: 
EUS: 
BRP: 
CIT: 
CIC: 
CICLE_v10001555mg CICLE_v10001661mg CICLE_v10003181mg CICLE_v10003323mg CICLE_v10003428mg CICLE_v10003445mg CICLE_v10003534mg CICLE_v10003737mg CICLE_v10005230mg CICLE_v10005251mg CICLE_v100108602m CICLE_v10012042mg CICLE_v10013542mg CICLE_v10015685mg CICLE_v10017649mg CICLE_v10017683mg CICLE_v10018226mg CICLE_v10018306mg CICLE_v10020377mg CICLE_v10020761mg CICLE_v10020782mg CICLE_v100208141m CICLE_v100208142m CICLE_v10020818mg CICLE_v10020820mg CICLE_v10020821mg CICLE_v10020828mg CICLE_v10020870mg CICLE_v10020873mg CICLE_v10020874mg CICLE_v10020875mg CICLE_v10020880mg CICLE_v10021670mg CICLE_v10021888mg CICLE_v10023459mg CICLE_v10023568mg CICLE_v10023965mg CICLE_v10023994mg CICLE_v10024037mg CICLE_v10024098mg CICLE_v10024389mg CICLE_v10026359mg CICLE_v10026361mg CICLE_v10031949mg CICLE_v10031951mg CICLE_v10031952mg CICLE_v10031953mg
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
POP: 
POPTR_0001s45530g(POPTRDRAFT_550470) POPTR_0002s07730g POPTR_0002s18120g POPTR_0002s18130g POPTR_0002s18150g(POPTRDRAFT_552360) POPTR_0002s18160g(POPTRDRAFT_799151) POPTR_0005s20630g POPTR_0011s15360g(POPTRDRAFT_806142) POPTR_0012s00670g(POPTRDRAFT_834247) POPTR_0014s10210g(POPTRDRAFT_774571) POPTR_0014s10220g(POPTRDRAFT_731466) POPTR_0015s00550g(POPTRDRAFT_824484) POPTR_0016s10450g POPTR_0019s11400g
VVI: 
SLY: 
SOT: 
DOSA: 
Os04t0104900-01(Os04g0104900) Os04t0175900-01(Os04g0175900) Os12t0199500-00(Os12g0199500) Os12t0240900-00(Os12g0240900)
OBR: 
BDI: 
SBI: 
SORBI_01g015803(SORBIDRAFT_01g015803) SORBI_01g033245(SORBIDRAFT_01g033245) SORBI_01g042900(SORBIDRAFT_01g042900) SORBI_07g004680(SORBIDRAFT_07g004680) SORBI_07g004690(SORBIDRAFT_07g004690) SORBI_07g004710(SORBIDRAFT_07g004710)
ZMA: 
SITA: 
PDA: 
MUS: 
ATR: 
s00001p00272250(AMTR_s00001p00272250)
SMO: 
PPP: 
 » show all
Taxonomy
Reference
1  [PMID:4472044]
  Authors
Ebel J, Schaller-Hekeler B, Knobloch KH, Wellman E, Grisebach H, Hahlbrock K.
  Title
Coordinated changes in enzyme activities of phenylpropanoid metabolism during the growth of soybean cell suspension cultures.
  Journal
Biochim. Biophys. Acta. 362 (1974) 417-24.
Reference
2  [PMID:241400]
  Authors
Poulton JE, Butt VS.
  Title
Purification and properties of S-adenosyl-L-methionine: caffeic acid O-methyltransferase from leaves of spinach beet (Beta vulgaris L).
  Journal
Biochim. Biophys. Acta. 403 (1975) 301-14.
Reference
3
  Authors
Shimada, M., Kuroda, H. and Higuchi, T.
  Title
Evidence for the formation of methoxyl groups of ferulic and sinapic acid in Bambusa by the same O-methyltransferase.
  Journal
Phytochemistry 12 (1973) 2873-2875.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
50936-45-3

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