KEGG   ENZYME: 2.1.1.68Help
Entry
EC 2.1.1.68                 Enzyme                                 

Name
caffeate O-methyltransferase;
caffeate methyltransferase;
caffeate 3-O-methyltransferase;
S-adenosyl-L-methionine:caffeic acid-O-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate [RN:R03366]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
3,4-dihydroxy-trans-cinnamate [CPD:C01197]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
3-methoxy-4-hydroxy-trans-cinnamate [CPD:C01494]
Comment
3,4-Dihydroxybenzaldehyde and catechol can act as acceptors, but more slowly.
History
EC 2.1.1.68 created 1984
Pathway
Phenylpropanoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K13066  
caffeic acid 3-O-methyltransferase
Genes
ATH: 
AT5G54160(OMT1)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
FVE: 
PPER: 
PMUM: 
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CSV: 
CMO: 
RCU: 
JCU: 
POP: 
POPTR_0001s45530g(POPTRDRAFT_550470) POPTR_0002s07730g POPTR_0002s18120g POPTR_0002s18130g POPTR_0002s18150g(POPTRDRAFT_552360) POPTR_0002s18160g(POPTRDRAFT_799151) POPTR_0005s20630g POPTR_0011s15360g(POPTRDRAFT_806142) POPTR_0012s00670g(POPTRDRAFT_834247) POPTR_0014s10210g(POPTRDRAFT_774571) POPTR_0014s10220g(POPTRDRAFT_731466) POPTR_0015s00550g(POPTRDRAFT_824484) POPTR_0016s10450g POPTR_0019s11400g
VVI: 
SLY: 
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SIND: 
BVG: 
NNU: 
DOSA: 
Os04t0175900-01(Os04g0175900) Os12t0199500-00(Os12g0199500) Os12t0240900-00(Os12g0240900)
OBR: 
BDI: 
SBI: 
SORBI_01g015803(SORBIDRAFT_01g015803) SORBI_01g033245(SORBIDRAFT_01g033245) SORBI_01g042900(SORBIDRAFT_01g042900) SORBI_07g004680(SORBIDRAFT_07g004680)
ZMA: 
100125646(comt) 101027166 103640406(GRMZM2G423331)
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
 » show all
Taxonomy
Reference
1  [PMID:4472044]
  Authors
Ebel J, Schaller-Hekeler B, Knobloch KH, Wellman E, Grisebach H, Hahlbrock K.
  Title
Coordinated changes in enzyme activities of phenylpropanoid metabolism during the growth of soybean cell suspension cultures.
  Journal
Biochim. Biophys. Acta. 362 (1974) 417-24.
Reference
2  [PMID:241400]
  Authors
Poulton JE, Butt VS.
  Title
Purification and properties of S-adenosyl-L-methionine: caffeic acid O-methyltransferase from leaves of spinach beet (Beta vulgaris L).
  Journal
Biochim. Biophys. Acta. 403 (1975) 301-14.
Reference
3
  Authors
Shimada, M., Kuroda, H. and Higuchi, T.
  Title
Evidence for the formation of methoxyl groups of ferulic and sinapic acid in Bambusa by the same O-methyltransferase.
  Journal
Phytochemistry 12 (1973) 2873-2875.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
50936-45-3

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