KEGG   ENZYME: 2.1.1.75Help
Entry
EC 2.1.1.75                 Enzyme                                 

Name
apigenin 4'-O-methyltransferase;
flavonoid O-methyltransferase;
flavonoid methyltransferase;
S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:apigenin 4'-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + apigenin = S-adenosyl-L-homocysteine + acacetin [RN:R03571]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
apigenin [CPD:C01477]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
acacetin [CPD:C01470]
Comment
Converts apigenin into acacetin. Naringenin can also act as an acceptor, but more slowly.
History
EC 2.1.1.75 created 1984
Pathway
Flavone and flavonol biosynthesis
Reference
1
  Authors
Kuroki, G. and Poulton, J.E.
  Title
The para-O-methylation of apigenin to acacetin by cell-free extracts of Robinia pseudoacacia L.
  Journal
Z. Naturforsch. C: Biosci. 36 (1981) 916-920.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
118251-36-8

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