| Entry |
|
|---|
| Name |
apigenin 4'-O-methyltransferase;
flavonoid O-methyltransferase;
flavonoid methyltransferase |
|---|
| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
|---|
| Sysname |
S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone
4'-O-methyltransferase |
|---|
| Reaction(IUBMB) |
S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone =
S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone
[RN:R03571] |
|---|
| Reaction(KEGG) |
R03571
 |
|---|
| Substrate |
S-adenosyl-L-methionine [CPD:C00019];
5,7,4'-trihydroxyflavone [CPD:C01477] |
|---|
| Product |
S-adenosyl-L-homocysteine [CPD:C00021];
4'-methoxy-5,7-dihydroxyflavone [CPD:C01470] |
|---|
| Comment |
Converts apigenin into acacetin. Naringenin
(5,7,4'-trihydroxy-flavanone) can also act as an acceptor, but more
slowly. |
|---|
| Pathway |
PATH: ec00944 Flavone and flavonol biosynthesis |
|---|
Reference
Authors
Title
Journal
|
1
Kuroki, G. and Poulton, J.E.
The para-O-methylation of apigenin to acacetin by cell-free extracts
of Robinia pseudoacacia L.
Z. Naturforsch. C: Biosci. 36 (1981) 916-920. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.1.75
IUBMB Enzyme Nomenclature: 2.1.1.75
ExPASy - ENZYME nomenclature database: 2.1.1.75
BRENDA, the Enzyme Database: 2.1.1.75
CAS: 118251-36-8 |
|---|
