| Entry |
|
|---|
| Name |
methylquercetagetin 6-O-methyltransferase;
flavonol 6-O-methyltransferase;
flavonol 6-methyltransferase;
6-OMT;
S-adenosyl-L-methionine:3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone
6-O-methyltransferase |
|---|
| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
|---|
| Sysname |
S-adenosyl-L-methionine:5,6,3',4'-tetrahydroxy-3,7-dimethoxyflavone
6-O-methyltransferase |
|---|
| Reaction(IUBMB) |
S-adenosyl-L-methionine +
5,6,3',4'-tetrahydroxy-3,7-dimethoxyflavone =
S-adenosyl-L-homocysteine +
5,3',4'-trihydroxy-3,6,7-trimethoxyflavone [RN:R04505] |
|---|
| Reaction(KEGG) |
R04505
 |
|---|
| Substrate |
S-adenosyl-L-methionine [CPD:C00019];
5,6,3',4'-tetrahydroxy-3,7-dimethoxyflavone |
|---|
| Product |
S-adenosyl-L-homocysteine [CPD:C00021];
5,3',4'-trihydroxy-3,6,7-trimethoxyflavone |
|---|
| Comment |
The enzymes from Chrysosplenium americanum also methylates
3,7,3'-trimethylquercetagetin at the 6-position. Does not act on
flavones, dihydroflavonols, or their glucosides. |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:3994393]
De Luca V, Ibrahim RK.
Enzymatic synthesis of polymethylated flavonols in Chrysosplenium
americanum. I. Partial purification and some properties of
S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and
4'-O-methyltransferases.
Arch. Biochem. Biophys. 238 (1985) 596-605.
Chrysosplenium americanum |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:3994394]
De Luca V, Ibrahim RK.
Enzymatic synthesis of polymethylated flavonols in Chrysosplenium
americanum. II. Substrate interaction and product inhibition studies
of flavonol 3-, 6-, and 4'-O-methyltransferases.
Arch. Biochem. Biophys. 238 (1985) 606-18.
Chrysosplenium americanum |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.1.84
IUBMB Enzyme Nomenclature: 2.1.1.84
ExPASy - ENZYME nomenclature database: 2.1.1.84
BRENDA, the Enzyme Database: 2.1.1.84
CAS: 97089-68-4 |
|---|
|
