| Entry |
|
|---|
| Name |
thiol S-methyltransferase;
S-methyltransferase;
thiol methyltransferase;
TMT |
|---|
| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
|---|
| Sysname |
S-adenosyl-L-methionine:thiol S-methyltransferase |
|---|
| Reaction(IUBMB) |
S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a
thioether [RN:R01235] |
|---|
| Reaction(KEGG) |
R01235;
(other) R04931
 |
|---|
| Substrate |
S-adenosyl-L-methionine [CPD:C00019];
thiol [CPD:C00145] |
|---|
| Product |
S-adenosyl-L-homocysteine [CPD:C00021];
thioether [CPD:C00297] |
|---|
| Comment |
H2S and a variety of alkyl, aryl and heterocyclic thiols and hydroxy
thiols can act as acceptors. |
|---|
| Pathway |
PATH: ec00450 Selenoamino acid metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:623768]
Borchardt RT, Cheng CF.
Purification and characterization of rat liver microsomal thiol
methyltransferase.
Biochim. Biophys. Acta. 522 (1978) 340-53.
Rattus norvegicus [GN:rno] |
|---|
Reference
Authors
Title
Journal
|
2
Bremer, J. and Greenberg, D.M.
Enzymic methylation of foreign sulfhydryl compounds.
Biochim. Biophys. Acta 46 (1961) 217-224. |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:485170]
Weisiger RA, Jakoby WB.
Thiol S-methyltransferase from rat liver.
Arch. Biochem. Biophys. 196 (1979) 631-7.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.1.9
IUBMB Enzyme Nomenclature: 2.1.1.9
ExPASy - ENZYME nomenclature database: 2.1.1.9
UM-BBD (Biocatalysis/Biodegradation Database): 2.1.1.9
BRENDA, the Enzyme Database: 2.1.1.9
CAS: 9029-81-6 |
|---|
