| Entry |
|
|---|
| Name |
methanol---5-hydroxybenzimidazolylcobamide Co-methyltransferase;
methanol cobalamin methyltransferase;
methanol:5-hydroxybenzimidazolylcobamide methyltransferase;
MT 1 |
|---|
| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
|---|
| Sysname |
methanol:5-hydroxybenzimidazolylcobamide Co-methyltransferase |
|---|
| Reaction(IUBMB) |
methanol + 5-hydroxybenzimidazolylcobamide =
Co-methyl-Co-5-hydroxybenzimidazolylcob(I)amide + H2O [RN:R04384] |
|---|
| Reaction(KEGG) |
R04384
 |
|---|
| Substrate |
methanol [CPD:C00132];
5-hydroxybenzimidazolylcobamide |
|---|
| Product |
Co-methyl-Co-5-hydroxybenzimidazolylcob(I)amide;
H2O [CPD:C00001] |
|---|
| Comment |
The enzyme from Methanosarcina barkeri contains three-four molecules
of bound 5-hydroxybenzimidazolylcobamide that act as methyl
acceptor. Inactivated by oxygen and other oxidizing agents, and
reactivated by catalytic amounts of ATP and hydrogen. |
|---|
| Orthology |
K04480 methanol---5-hydroxybenzimidazolylcobamide
Co-methyltransferase |
|---|
| Genes |
RCI: RCIX1973(mtaC) RCIX1974(mtaB)
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6438059]
van der Meijden P, te Brommelstroet BW, Poirot CM, van der Drift C,
Vogels GD.
Purification and properties of
methanol:5-hydroxybenzimidazolylcobamide methyltransferase from
Methanosarcina barkeri.
J. Bacteriol. 160 (1984) 629-35.
Methanosarcina barkeri [GN:mba] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.1.90
IUBMB Enzyme Nomenclature: 2.1.1.90
ExPASy - ENZYME nomenclature database: 2.1.1.90
BRENDA, the Enzyme Database: 2.1.1.90
CAS: 86611-98-5 |
|---|
