KEGG   ENZYME: 2.1.1.97Help
Entry
EC 2.1.1.97                 Enzyme                                 

Name
3-hydroxyanthranilate 4-C-methyltransferase;
3-hydroxyanthranilate 4-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 3-hydroxyanthranilate = S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate [RN:R02667]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
3-hydroxyanthranilate [CPD:C00632]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
3-hydroxy-4-methylanthranilate [CPD:C03986]
Comment
Involved in the biosynthesis of the antibiotic actinomycin in Streptomyces antibioticus.
History
EC 2.1.1.97 created 1990
Reference
1  [PMID:2450873]
  Authors
Fawaz F, Jones GH.
  Title
Actinomycin synthesis in Streptomyces antibioticus. Purification and properties of a 3-hydroxyanthranilate 4-methyltransferase.
  Journal
J. Biol. Chem. 263 (1988) 4602-6.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
112445-22-4

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