KEGG   ENZYME: 2.1.2.4Help
Entry
EC 2.1.2.4                  Enzyme                                 

Name
glycine formimidoyltransferase;
formiminoglycine formiminotransferase;
FIG formiminotransferase;
glycine formiminotransferase
Class
Transferases;
Transferring one-carbon groups;
Hydroxymethyl-, formyl- and related transferases
BRITE hierarchy
Sysname
5-formimidoyltetrahydrofolate:glycine N-formimidoyltransferase
Reaction(IUBMB)
5-formimidoyltetrahydrofolate + glycine = tetrahydrofolate + N-formimidoylglycine [RN:R02729]
Reaction(KEGG)
Substrate
5-formimidoyltetrahydrofolate [CPD:C00664];
glycine [CPD:C00037]
Product
tetrahydrofolate [CPD:C00101];
N-formimidoylglycine [CPD:C02718]
History
EC 2.1.2.4 created 1961, modified 2000
Pathway
Purine metabolism
One carbon pool by folate
Metabolic pathways
Reference
1
  Authors
Rabinowitz, J.C. and Pricer, W.E.
  Title
Formiminotetrahydrofolic acid and methenyltetrahydrofolic acid as intermediates in the formation of N10-formyltetrahydrofolic acid.
  Journal
J. Am. Chem. Soc. 78 (1956) 5702-5704.
Reference
2
  Authors
Rabinowitz, J.C. and Pricer, W.E.
  Title
Formation, isolation and properties of 5-formiminotetrahydrofolic acid.
  Journal
Fed. Proc. 16 (1957) 236.
Reference
3
  Authors
Sagers, R.D., Beck, J.V., Gruber, W. and Gunsalus, I.C.
  Title
A tetrahydrofolic acid linked formimino transfer enzyme.
  Journal
J. Am. Chem. Soc. 78 (1956) 694-695.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9029-84-9

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