KEGG   ENZYME: 2.1.3.9Help
Entry
EC 2.1.3.9                  Enzyme                                 

Name
N-acetylornithine carbamoyltransferase;
acetylornithine transcarbamylase;
N-acetylornithine transcarbamylase;
AOTC;
carbamoyl-phosphate:2-N-acetyl-L-ornithine carbamoyltransferase;
AOTCase
Class
Transferases;
Transferring one-carbon groups;
Carboxy- and carbamoyltransferases
BRITE hierarchy
Sysname
carbamoyl-phosphate:N2-acetyl-L-ornithine carbamoyltransferase
Reaction(IUBMB)
carbamoyl phosphate + N2-acetyl-L-ornithine = phosphate + N-acetyl-L-citrulline [RN:R07245]
Reaction(KEGG)
Substrate
carbamoyl phosphate [CPD:C00169];
N2-acetyl-L-ornithine [CPD:C00437]
Product
phosphate [CPD:C00009];
N-acetyl-L-citrulline [CPD:C15532]
Comment
Differs from EC 2.1.3.3, ornithine carbamoyltransferase. This enzyme replaces EC 2.1.3.3 in the canonic arginine biosynthetic pathway of several Eubacteria and has no catalytic activity with L-ornithine as substrate.
History
EC 2.1.3.9 created 2005
Pathway
Arginine biosynthesis
Metabolic pathways
Orthology
K09065  
N-acetylornithine carbamoyltransferase
Genes
XFA: 
XFT: 
PD_0290(argF)
XFM: 
XFN: 
XFF: 
XFL: 
XFS: 
XCC: 
XCC2249(argF)
XCB: 
XCA: 
XCP: 
XCV: 
XCV2551(argF)
XAC: 
XAC2352(argF)
XCI: 
XCT: 
XCU: 
XCN: 
XCW: 
XCR: 
XCM: 
XCF: 
XCJ: 
XFU: 
XAX: 
XACM_2361(argF)
XAO: 
XOO: 
XOO2676(argF)
XOM: 
XOO2522(XOO2522)
XOP: 
XOY: 
XOR: 
XOZ: 
XAL: 
XALC_1896(argF)
XSA: 
XTN: 
SML: 
SMT: 
BUJ: 
SMZ: 
SACZ: 
AOT14_15980(pyrB_2)
STEK: 
SRH: 
PSU: 
PSUW: 
PSD: 
LAB: 
LAQ: 
LCP: 
LGU: 
LEZ: 
FAU: 
RHD: 
DJI: 
DJA: 
DTX: 
DKO: 
WMA: 
WOC: 
KKO: 
KGE: 
KSD: 
SDF: 
PPK: 
PPNO: 
PPNM: 
PRB: 
PPUL: 
PSPU: 
PAPI: 
PVE: 
POX: 
PFG: 
MXA: 
MXAN_5104(argF)
MFU: 
MSD: 
MYM: 
CCX: 
SUR: 
SCL: 
sce0074(argF1)
SCU: 
CCRO: 
LLU: 
MMR: 
PBR: 
MTA: 
ATM: 
ABAO: 
CAP: 
CTM: 
SRU: 
SRM: 
SRM_02445(argF)
RMR: 
RMG: 
BARC: 
AOA65_0973(argF_2)
 » show all
Taxonomy
Reference
1  [PMID:15731101]
  Authors
Shi D, Morizono H, Yu X, Roth L, Caldovic L, Allewell NM, Malamy MH, Tuchman M.
  Title
Crystal structure of N-acetylornithine transcarbamylase from Xanthomonas campestris: a novel enzyme in a new arginine biosynthetic pathway found in several eubacteria.
  Journal
J. Biol. Chem. 280 (2005) 14366-9.
  Sequence
[xcc:XCC2249]
Reference
2  [PMID:16585758]
  Authors
Morizono H, Cabrera-Luque J, Shi D, Gallegos R, Yamaguchi S, Yu X, Allewell NM, Malamy MH, Tuchman M.
  Title
Acetylornithine transcarbamylase: a novel enzyme in arginine biosynthesis.
  Journal
J. Bacteriol. 188 (2006) 2974-82.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
890853-54-0

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