KEGG   ENZYME: 2.1.4.2Help
Entry
EC 2.1.4.2                  Enzyme                                 

Name
scyllo-inosamine-4-phosphate amidinotransferase;
L-arginine:inosamine-P-amidinotransferase;
inosamine-P amidinotransferase;
L-arginine:inosamine phosphate amidinotransferase;
inosamine-phosphate amidinotransferase
Class
Transferases;
Transferring one-carbon groups;
Amidinotransferases
BRITE hierarchy
Sysname
L-arginine:1-amino-1-deoxy-scyllo-inositol-4-phosphate amidinotransferase
Reaction(IUBMB)
L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate = L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate [RN:R03477]
Reaction(KEGG)
Substrate
L-arginine [CPD:C00062];
1-amino-1-deoxy-scyllo-inositol 4-phosphate [CPD:C01283]
Product
L-ornithine [CPD:C00077];
1-guanidino-1-deoxy-scyllo-inositol 4-phosphate [CPD:C01294]
Comment
1D-1-Guanidino-3-amino-1,3-dideoxy-scyllo-inositol 6-phosphate, streptamine phosphate and 2-deoxystreptamine phosphate can also act as acceptors; canavanine can act as donor.
History
EC 2.1.4.2 created 1976, modified 2001
Pathway
Streptomycin biosynthesis
Biosynthesis of antibiotics
Orthology
K04340  
scyllo-inosamine-4-phosphate amidinotransferase 1
Genes
SGR: 
SGR_5933(strB1)
SBH: 
Taxonomy
Reference
1  [PMID:5935341]
  Authors
Walker MS, Walker JB.
  Title
Enzymic studies on the biosynthesis of streptomycin. Transamidination of inosamine and streptamine derivatives.
  Journal
J. Biol. Chem. 241 (1966) 1262-70.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
52227-63-1

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