KEGG   ENZYME: 2.2.1.3Help
Entry
EC 2.2.1.3                  Enzyme                                 

Name
formaldehyde transketolase;
dihydroxyacetone synthase
Class
Transferases;
Transferring aldehyde or ketonic groups;
Transketolases and transaldolases
BRITE hierarchy
Sysname
D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase
Reaction(IUBMB)
D-xylulose 5-phosphate + formaldehyde = D-glyceraldehyde 3-phosphate + glycerone [RN:R01440]
Reaction(KEGG)
R01440;
(other) R06861 R06862
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Substrate
D-xylulose 5-phosphate [CPD:C00231];
formaldehyde [CPD:C00067]
Product
D-glyceraldehyde 3-phosphate [CPD:C00118];
glycerone [CPD:C00184]
Comment
A thiamine-diphosphate protein. Not identical with EC 2.2.1.1 transketolase. Also converts hydroxypyruvate and formaldehyde into glycerone and CO2.
History
EC 2.2.1.3 created 1984
Pathway
Methane metabolism
Microbial metabolism in diverse environments
Orthology
K17100  
dihydroxyacetone synthase
Genes
PPA: 
DHA: 
PIC: 
PGU: 
MGR: 
FGR: 
NHE: 
TRE: 
VAL: 
BFU: 
ANI: 
AFM: 
AOR: 
AOR_1_562164(AO090001000322) AOR_1_592144(AO090023000345)
ANG: 
ANI_1_510124(An14g03500)
AFV: 
NFI: 
PCS: 
PNO: 
PTE: 
ZTR: 
CNE: 
CNB: 
CGI: 
SCM: 
 » show all
Taxonomy
Reference
1  [PMID:7249920]
  Authors
Bystrykh LV, Sokolov AP, Trotsenko IuA.
  Title
[Separation of transketolase and dihydroxyacetone synthase from methylotrophic yeasts]
  Journal
Dokl. Akad. Nauk. SSSR. 258 (1981) 499-501.
Reference
2  [PMID:7074134]
  Authors
Kato N, Higuchi T, Sakazawa C, Nishizawa T, Tani Y, Yamada H.
  Title
Purification and properties of a transketolase responsible for formaldehyde fixation in a methanol-utilizing yeast, candida boidinii (Kloeckera sp.) No. 2201.
  Journal
Biochim. Biophys. Acta. 715 (1982) 143-50.
  Organism
Candida boidinii
Reference
3  [PMID:6276498]
  Authors
Waites MJ, Quayle JR.
  Title
The interrelation transketolase and dihydroxyacetone synthase activities in the methylotrophic yeast Candida boidinii.
  Journal
J. Gen. Microbiol. 124 (1981) 309-16.
  Organism
Candida boidinii
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
124566-23-0

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