KEGG   ENZYME: 2.2.1.3Help
Entry
EC 2.2.1.3                  Enzyme                                 

Name
formaldehyde transketolase;
dihydroxyacetone synthase
Class
Transferases;
Transferring aldehyde or ketonic groups;
Transketolases and transaldolases
BRITE hierarchy
Sysname
D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase
Reaction(IUBMB)
D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + glycerone [RN:R01440]
Reaction(KEGG)
R01440;
(other) R06861 R06862
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Substrate
D-xylulose 5-phosphate [CPD:C00231];
formaldehyde [CPD:C00067]
Product
glyceraldehyde 3-phosphate [CPD:C00118];
glycerone [CPD:C00184]
Comment
A thiamine-diphosphate protein. Not identical with EC 2.2.1.1 transketolase. Also converts hydroxypyruvate and formaldehyde into glycerone and CO2.
Pathway
Methane metabolism
Microbial metabolism in diverse environments
Reference
1  [PMID:7249920]
  Authors
Bystrykh LV, Sokolov AP, Trotsenko IuA.
  Title
[Separation of transketolase and dihydroxyacetone synthase from methylotrophic yeasts]
  Journal
Dokl. Akad. Nauk. SSSR. 258 (1981) 499-501.
Reference
2  [PMID:7074134]
  Authors
Kato N, Higuchi T, Sakazawa C, Nishizawa T, Tani Y, Yamada H.
  Title
Purification and properties of a transketolase responsible for formaldehyde fixation in a methanol-utilizing yeast, candida boidinii (Kloeckera sp.) No. 2201.
  Journal
Biochim. Biophys. Acta. 715 (1982) 143-50.
  Organism
Candida boidinii
Reference
3  [PMID:6276498]
  Authors
Waites MJ, Quayle JR.
  Title
The interrelation transketolase and dihydroxyacetone synthase activities in the methylotrophic yeast Candida boidinii.
  Journal
J. Gen. Microbiol. 124 (1981) 309-16.
  Organism
Candida boidinii
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
124566-23-0

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