| Entry |
|
|---|
| Name |
formylmethanofuran---tetrahydromethanopterin N-formyltransferase;
formylmethanofuran-tetrahydromethanopterin formyltransferase;
formylmethanofuran:tetrahydromethanopterin formyltransferase;
N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT)
formyltransferase;
FTR;
formylmethanofuran:5,6,7,8-tetrahydromethanopterin
N5-formyltransferase |
|---|
| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
 |
|---|
| Sysname |
formylmethanofuran:5,6,7,8-tetrahydromethanopterin
5-formyltransferase |
|---|
| Reaction(IUBMB) |
formylmethanofuran + 5,6,7,8-tetrahydromethanopterin = methanofuran
+ 5-formyl-5,6,7,8-tetrahydromethanopterin [RN:R03390] |
|---|
| Reaction(KEGG) |
R03390
 |
|---|
| Substrate |
formylmethanofuran [CPD:C01001];
5,6,7,8-tetrahydromethanopterin [CPD:C01217] |
|---|
| Product |
methanofuran [CPD:C00862];
5-formyl-5,6,7,8-tetrahydromethanopterin [CPD:C01274] |
|---|
| Comment |
Methanofuran is a complex 4-substituted furfurylamine and is
involved in the formation of methane from CO2 in Methanobacterium
thermoautotrophicum. |
|---|
| Pathway |
PATH: ec00680 Methane metabolism
PATH: ec00790 Folate biosynthesis
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00672 formylmethanofuran--tetrahydromethanopterin
N-formyltransferase |
|---|
| Genes |
MCA: MCA2858
NOC: Noc_0023
BXE: Bxe_B2463(fhcD)
BPH: Bphy_5933 Bphy_6506
VAP: Vapar_3065
MPT: Mpe_A2625
LCH: Lcho_3134
MFA: Mfla_1664
MMB: Mmol_0859
MEI: Msip34_1508
XAU: Xaut_1794
MEX: Mext_1825
MEA: Mex_1p1756(fhcD)
MDI: METDI2508(fhcD)
MRD: Mrad2831_0524
MET: M446_5774
MPO: Mpop_1776
MCH: Mchl_2160
MNO: Mnod_5998
MSL: Msil_2402
GBE: GbCGDNIH1_0780
RBA: RB9835(ffsA)
MJA: MJ0318
MFE: Mefer_1275
MVU: Metvu_0497
MMP: MMP1609(ftr)
MMQ: MmarC5_1799
MMX: MmarC6_1060
MMZ: MmarC7_0857
MAE: Maeo_0224
MVN: Mevan_0919
MAC: MA0010(ftr)
MBA: Mbar_A0980
MMA: MM_1321
MBU: Mbur_1728
MTP: Mthe_1643
MHU: Mhun_1808
MLA: Mlab_0215
MEM: Memar_0628
MBN: Mboo_0593
MPL: Mpal_2244
MPD: MCP_1033(ftr)
MTH: MTH1259 MTH403
MST: Msp_0070(ftr2) Msp_1502(ftr1)
MSI: Msm_0308 Msm_1092
MKA: MK0116(ftr_1) MK0816(ftr_2)
AFU: AF2073(ftr-1) AF2207(ftr-2)
RCI: LRC202(ftr)
 |
|---|
| Structures |
PDB: 1FTR 1M5H 1M5S 2FHJ 2FHK |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:3097011]
Donnelly MI, Wolfe RS.
The role of formylmethanofuran: tetrahydromethanopterin
formyltransferase in methanogenesis from carbon dioxide.
J. Biol. Chem. 261 (1986) 16653-9.
Methanobacterium thermoautotrophicum [GN:mth] |
|---|
Reference
Authors
Title
Journal
|
2
Leigh, J.A., Rinehart, K.L. and Wolfe, R.S.
Structure of methanofuran, the carbon-dioxide reduction factor of
Methanobacterium thermoautotrophicum.
J. Am. Chem. Soc. 106 (1984) 3636-3640. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.3.1.101
IUBMB Enzyme Nomenclature: 2.3.1.101
ExPASy - ENZYME nomenclature database: 2.3.1.101
UM-BBD (Biocatalysis/Biodegradation Database): 2.3.1.101
BRENDA, the Enzyme Database: 2.3.1.101
CAS: 105669-83-8 |
|---|
