KEGG   ENZYME: 2.3.1.101Help
Entry
EC 2.3.1.101                Enzyme                                 

Name
formylmethanofuran---tetrahydromethanopterin N-formyltransferase;
formylmethanofuran-tetrahydromethanopterin formyltransferase;
formylmethanofuran:tetrahydromethanopterin formyltransferase;
N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase;
FTR;
formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
formylmethanofuran:5,6,7,8-tetrahydromethanopterin 5-formyltransferase
Reaction(IUBMB)
formylmethanofuran + 5,6,7,8-tetrahydromethanopterin = methanofuran + 5-formyl-5,6,7,8-tetrahydromethanopterin [RN:R03390]
Reaction(KEGG)
Substrate
formylmethanofuran [CPD:C01001];
5,6,7,8-tetrahydromethanopterin [CPD:C01217]
Product
methanofuran [CPD:C00862];
5-formyl-5,6,7,8-tetrahydromethanopterin [CPD:C01274]
Comment
Methanofuran is a complex 4-substituted furfurylamine and is involved in the formation of methane from CO2 in Methanobacterium thermoautotrophicum.
History
EC 2.3.1.101 created 1989
Pathway
Methane metabolism
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K00672  
formylmethanofuran--tetrahydromethanopterin N-formyltransferase
Genes
MCA: 
MMT: 
MDN: 
MDH: 
MAH: 
MEJ: 
MEC: 
TIG: 
BLEP: 
NOC: 
NHL: 
NWA: 
SEDS: 
BUG: 
BGE: 
BGF: 
BYI: 
BUO: 
BUE: 
BUQ: 
BXE: 
Bxe_B2463(fhcD)
BXB: 
DR64_4790(fhcD)
BPH: 
BPX: 
BCAI: 
VAP: 
VPD: 
MPT: 
LCH: 
RGE: 
RGE_40410(fhcD)
AZA: 
THU: 
METR: 
MFA: 
MMB: 
MEH: 
MEI: 
MEP: 
MBAC: 
MEU: 
MCI: 
RGA: 
XAU: 
SNO: 
MEX: 
MEA: 
MDI: 
METDI2508(fhcD)
MCH: 
MRD: 
MET: 
MPO: 
MNO: 
MOR: 
MOC_0679(fhcD)
META: 
MAQU: 
MSL: 
HDN: 
HDT: 
HMC: 
HNI: 
FIL: 
FIY: 
MSC: 
MCG: 
GBE: 
GBH: 
GBC: 
GBS: 
ALI: 
ABS: 
ABQ: 
ATI: 
HAS: 
RBA: 
RB9835(ffsA)
PSL: 
PIR: 
VN12_16340(fhcD_1) VN12_25910(fhcD_2)
PLM: 
PBS: 
PLS: 
VT03_25050(fhcD_1) VT03_26560(fhcD_2)
PLH: 
GES: 
VT84_05645(fhcD_1) VT84_15260(fhcD_2)
IPA: 
SACI: 
AMO: 
MOX: 
DAMO_0459(fhcD)
MJA: 
MFE: 
MVU: 
MFS: 
MIF: 
MJH: 
MIG: 
MMP: 
MMP1609(ftr)
MMQ: 
MMX: 
MMZ: 
MMD: 
MMAK: 
MMAO: 
MAE: 
MVN: 
MVO: 
MOK: 
MAC: 
MA_0010(ftr)
MBA: 
MBY: 
MBW: 
MBAR: 
MBAK: 
MMA: 
MMAZ: 
MMJ: 
MVC: 
MEK: 
MLS: 
METM: 
MEF: 
MEQ: 
MSJ: 
MSZ: 
MSW: 
MTHE: 
MTHR: 
MHOR: 
MBU: 
MMET: 
MMH: 
MEV: 
MZH: 
MPY: 
MHZ: 
MTP: 
MCJ: 
MCON_1472(fhcD)
MHI: 
MHU: 
MLA: 
MEM: 
MBG: 
MEMA: 
MPI: 
MBN: 
MFO: 
MPL: 
MPD: 
MEZ: 
RCI: 
LRC202(ftr)
MTH: 
MMG: 
METC: 
MST: 
Msp_0070(ftr2) Msp_1502(ftr1)
MSI: 
MRU: 
mru_1393(ftr1) mru_2022(ftr2)
MEB: 
Abm4_0936(ftr1) Abm4_1598(ftr2)
MMIL: 
sm9_0727(ftr1) sm9_2108(ftr2)
MEYE: 
MOL: 
MEL: 
MEW: 
METH: 
MFC: 
BRM9_1337(ftr) BRM9_2162(ftr2)
MFI: 
MCUB: 
MCBB_1014(ehaS) MCBB_2124(ftr)
MFV: 
MKA: 
MK0116(ftr_1) MK0816(ftr_2)
AFU: 
AFG: 
APO: 
AVE: 
AST: 
FPL: 
GAC: 
GAH: 
LOKI: 
BARC: 
AOA65_1220(ftr_1) AOA65_2064(ftr_2)
BARB: 
 » show all
Taxonomy
Reference
1  [PMID:3097011]
  Authors
Donnelly MI, Wolfe RS.
  Title
The role of formylmethanofuran: tetrahydromethanopterin formyltransferase in methanogenesis from carbon dioxide.
  Journal
J. Biol. Chem. 261 (1986) 16653-9.
Reference
2
  Authors
Leigh, J.A., Rinehart, K.L. and Wolfe, R.S.
  Title
Structure of methanofuran, the carbon-dioxide reduction factor of Methanobacterium thermoautotrophicum.
  Journal
J. Am. Chem. Soc. 106 (1984) 3636-3640.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
105669-83-8

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