| Entry |
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| Name |
alkylglycerophosphate 2-O-acetyltransferase;
alkyllyso-GP:acetyl-CoA acetyltransferase
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| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
 |
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| Sysname |
acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase
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| Reaction(IUBMB) |
acetyl-CoA + 1-alkyl-sn-glycero-3-phosphate = CoA + 1-alkyl-2-acetyl-sn-glycero-3-phosphate [RN: R03455]
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| Reaction(KEGG) |
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| Substrate |
acetyl-CoA [CPD: C00024];
1-alkyl-sn-glycero-3-phosphate [CPD: C03968]
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| Product |
CoA [CPD: C00010];
1-alkyl-2-acetyl-sn-glycero-3-phosphate
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| Comment |
Involved in the biosynthesis of thrombocyte activating factor in animal tissues.
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| Pathway |
| Ether lipid metabolism | | Metabolic pathways |
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| Reference |
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| Authors |
Lee TC, Malone B, Snyder F. |
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| Title |
A new de novo pathway for the formation of 1-alkyl-2-acetyl-sn-glycerols, precursors of platelet activating factor. Biochemical characterization of 1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase in rat spleen. |
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| Journal |
J. Biol. Chem. 261 (1986) 5373-7. |
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| Organism |
Rattus norvegicus [GN: rno] |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: |
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