KEGG   ENZYME: 2.3.1.105Help
Entry
EC 2.3.1.105                Enzyme                                 

Name
alkylglycerophosphate 2-O-acetyltransferase;
alkyllyso-GP:acetyl-CoA acetyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + 1-alkyl-sn-glycero-3-phosphate = CoA + 1-alkyl-2-acetyl-sn-glycero-3-phosphate [RN:R03455]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
1-alkyl-sn-glycero-3-phosphate [CPD:C03968]
Product
CoA [CPD:C00010];
1-alkyl-2-acetyl-sn-glycero-3-phosphate
Comment
Involved in the biosynthesis of thrombocyte activating factor in animal tissues.
History
EC 2.3.1.105 created 1989
Pathway
Ether lipid metabolism
Metabolic pathways
Reference
1  [PMID:3007498]
  Authors
Lee TC, Malone B, Snyder F.
  Title
A new de novo pathway for the formation of 1-alkyl-2-acetyl-sn-glycerols, precursors of platelet activating factor. Biochemical characterization of 1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase in rat spleen.
  Journal
J. Biol. Chem. 261 (1986) 5373-7.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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