Entry |
|
Name |
1-alkyl-2-acetylglycerol O-acyltransferase;
1-hexadecyl-2-acetylglycerol acyltransferase
|
Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
 |
Sysname |
acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol O-acyltransferase
|
Reaction(IUBMB) |
acyl-CoA + 1-O-alkyl-2-acetyl-sn-glycerol = CoA + 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol [RN: R04363]
|
Reaction(KEGG) |
|
Substrate |
acyl-CoA [CPD: C00040];
1-O-alkyl-2-acetyl-sn-glycerol [CPD: C03820]
|
Product |
CoA [CPD: C00010];
1-O-alkyl-2-acetyl-3-acyl-sn-glycerol [CPD: C04361]
|
Comment |
A number of acyl-CoAs can act as acyl donor; maximum activity is obtained with linoleoyl-CoA. Not identical with EC 2.3.1.20 diacylglycerol O-acyltransferase.
|
History |
EC 2.3.1.125 created 1990
|
Pathway |
|
Reference |
|
Authors |
Kawasaki T, Snyder F. |
Title |
Synthesis of a novel acetylated neutral lipid related to platelet-activating factor by acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol acyltransferase in HL-60 cells. |
Journal |
J. Biol. Chem. 263 (1988) 2593-6. |
Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 114704-90-4 |