| Entry |
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| Name |
1-alkyl-2-acetylglycerol O-acyltransferase;
1-hexadecyl-2-acetylglycerol acyltransferase
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| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
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| Sysname |
acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol O-acyltransferase
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| Reaction(IUBMB) |
acyl-CoA + 1-O-alkyl-2-acetyl-sn-glycerol = CoA + 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol [RN: R04363]
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| Reaction(KEGG) |
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| Substrate |
acyl-CoA [CPD: C00040];
1-O-alkyl-2-acetyl-sn-glycerol [CPD: C03820]
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| Product |
CoA [CPD: C00010];
1-O-alkyl-2-acetyl-3-acyl-sn-glycerol [CPD: C04361]
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| Comment |
A number of acyl-CoAs can act as acyl donor; maximum activity is obtained with linoleoyl-CoA. Not identical with EC 2.3.1.20 diacylglycerol O-acyltransferase.
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| History |
EC 2.3.1.125 created 1990
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| Pathway |
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| Reference |
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| Authors |
Kawasaki T, Snyder F. |
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| Title |
Synthesis of a novel acetylated neutral lipid related to platelet-activating factor by acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol acyltransferase in HL-60 cells. |
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| Journal |
J. Biol. Chem. 263 (1988) 2593-6. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 114704-90-4 |
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