KEGG   ENZYME: 2.3.1.13Help
Entry
EC 2.3.1.13                 Enzyme                                 

Name
glycine N-acyltransferase;
glycine acyltransferase;
glycine-N-acylase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acyl-CoA:glycine N-acyltransferase
Reaction(IUBMB)
acyl-CoA + glycine = CoA + N-acylglycine [RN:R00395]
Reaction(KEGG)
Substrate
acyl-CoA [CPD:C00040];
glycine [CPD:C00037]
Product
CoA [CPD:C00010];
N-acylglycine [CPD:C02055]
Comment
The CoA derivatives of a number of aliphatic and aromatic acids, but not phenylacetyl-CoA or (indol-3-yl)acetyl-CoA, can act as donor. Not identical with EC 2.3.1.68 glutamine N-acyltransferase or EC 2.3.1.71 glycine N-benzoyltransferase.
History
EC 2.3.1.13 created 1961
Pathway
Phenylalanine metabolism
Orthology
K00628  
glycine N-acyltransferase
Genes
HSA: 
10249(GLYAT)
PTR: 
748398(GLYAT)
PPS: 
100980359(GLYAT)
GGO: 
101124654(GLYAT)
PON: 
100173810(GLYAT)
NLE: 
MCC: 
701659(GLYAT)
MCF: 
CSAB: 
103235080(GLYAT)
RRO: 
104680418(GLYAT)
CJC: 
100395000(GLYAT)
SBQ: 
101033622(GLYAT)
MMU: 
107146(Glyat) 64697(Keg1)
RNO: 
171179(Glyatl2) 293779(Glyat)
CGE: 
NGI: 
HGL: 
OCU: 
100345309(GLYAT)
TUP: 
CFA: 
483463(GLYAT)
AML: 
UMR: 
103666140(GLYAT)
FCA: 
101097840(GLYAT)
PTG: 
102966010(GLYAT)
BTA: 
281787(GLYAT)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
CFR: 
BACU: 
LVE: 
ECB: 
100066603(GLYAT)
MYB: 
MYD: 
PALE: 
LAV: 
MDO: 
100027219(GLYAT)
SHR: 
100918927(GLYAT)
OAA: 
100081664(GLYAT)
MZE: 
XMA: 
SKO: 
 » show all
Taxonomy
Reference
1  [PMID:457678]
  Authors
Nandi DL, Lucas SV, Webster LT Jr.
  Title
Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization.
  Journal
J. Biol. Chem. 254 (1979) 7230-7.
  Sequence
[bta:281787]
Reference
2  [PMID:13174534]
  Authors
SCHACHTER D, TAGGART JV.
  Title
Glycine N-acylase: purification and properties.
  Journal
J. Biol. Chem. 208 (1954) 263-75.
Reference
3  [PMID:931988]
  Authors
Webster LT, Siddiqui UA, Lucas SV, Strong JM, Mieyal JJ.
  Title
Identification of separate acyl- CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man.
  Journal
J. Biol. Chem. 251 (1976) 3352-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9029-95-2

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