KEGG   ENZYME: 2.3.1.158Help
Entry
EC 2.3.1.158                Enzyme                                 

Name
phospholipid:diacylglycerol acyltransferase;
PDAT
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase
Reaction(IUBMB)
phospholipid + 1,2-diacyl-sn-glycerol = lysophospholipid + triacylglycerol [RN:R05333]
Reaction(KEGG)
Substrate
phospholipid [CPD:C00865];
1,2-diacyl-sn-glycerol [CPD:C00641]
Product
lysophospholipid [CPD:C06254];
triacylglycerol [CPD:C00422]
Comment
This enzyme differs from EC 2.3.1.20, diacylglycerol O-acyltransferase, by synthesising triacylglycerol using an acyl-CoA-independent mechanism. The specificity of the enzyme for the acyl group in the phospholipid varies with species, e.g., the enzyme from castor bean (Ricinus communis) preferentially incorporates vernoloyl (12,13-epoxyoctadec-9-enoyl) groups into triacylglycerol, whereas that from the hawk's beard (Crepis palaestina) incorporates both ricinoleoyl (12-hydroxyoctadec-9-enoyl) and vernoloyl groups. The enzyme from the yeast Saccharomyces cerevisiae specifically transfers acyl groups from the sn-2 position of the phospholipid to diacylglycerol, thus forming an sn-1-lysophospholipid.
History
EC 2.3.1.158 created 2001
Pathway
Glycerolipid metabolism
Orthology
K00679  
phospholipid:diacylglycerol acyltransferase
Genes
ATH: 
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj3g3v2656650.1(Lj3g3v2656650.1) Lj4g3v2179270.1(Lj4g3v2179270.1)
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
8266990(PDAT2) 8272509(PDAT1-2) 8284674(PDAT)
JCU: 
POP: 
POPTR_0001s17100g(POPTRDRAFT_751462) POPTR_0003s06140g(POPTRDRAFT_854288) POPTR_0004s20140g
VVI: 
SLY: 
SPEN: 
SOT: 
SIND: 
BVG: 
NNU: 
OSA: 
4347190(OJ1123_B08.7-1)
DOSA: 
Os09t0444200-01(Os09g0444200)
OBR: 
BDI: 
ATS: 
SBI: 
SORBI_02g026010(SORBIDRAFT_02g026010)
ZMA: 
100191489(TIDP3675) 100273525(pco139319) 103652403
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OTA: 
BPG: 
MIS: 
MPP: 
CSL: 
SCE: 
YNR008W(LRO1)
AGO: 
ERC: 
KLA: 
LTH: 
ZRO: 
CGR: 
NCS: 
NCAS_0G00980(NCAS0G00980)
NDI: 
NDAI_0F01110(NDAI0F01110)
TPF: 
TPHA_0D03660(TPHA0D03660)
TBL: 
TBLA_0A02430(TBLA0A02430)
TDL: 
TDEL_0A07120(TDEL0A07120)
KAF: 
KAFR_0F00910(KAFR0F00910)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CTP: 
COT: 
CDU: 
CTEN: 
YLI: 
CLU: 
NCR: 
NTE: 
NEUTE1DRAFT85933(NEUTE1DRAFT_85933)
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
FPU: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
VDA: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_900154(AO090003000514)
ANG: 
ANI_1_1660144(An16g03640)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
PBN: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
DSQ: 
PCO: 
SHS: 
HIR: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MPR: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT71227(AGABI1DRAFT_71227)
ABV: 
AGABI2DRAFT204119(AGABI2DRAFT_204119)
CPUT: 
SLA: 
WSE: 
WIC: 
UMA: 
PFP: 
MGL: 
PGR: 
MLR: 
SRE: 
EHI: 
EHI_099180(57.t00020)
EDI: 
ACAN: 
SMIN: 
v1.2.037941.t1(symbB.v1.2.037941.t1)
PTI: 
TPS: 
AAF: 
PIF: 
PSOJ: 
SPAR: 
EHX: 
GTT: 
TBR: 
TCR: 
LMA: 
LIF: 
LDO: 
LMI: 
LBZ: 
 » show all
Taxonomy
Reference
1  [PMID:10829075]
  Authors
Dahlqvist A, Stahl U, Lenman M, Banas A, Lee M, Sandager L, Ronne H, Stymne S.
  Title
Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 6487-92.
  Sequence
[sce:YNR008W]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
288587-47-3

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