acetoin dehydrogenase;
acetoin dehydrogenase complex;
acetoin dehydrogenase enzyme system;
AoDH ES

Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups

acetyl-CoA:acetoin O-acetyltransferase

acetoin + CoA + NAD+ = acetaldehyde + acetyl-CoA + NADH + H+ [RN:R09524]

R09524

acetoin [CPD:C00466];
CoA [CPD:C00010];
NAD+ [CPD:C00003]

Requires thiamine diphosphate. This enzyme, which belongs to the family of 2-oxo acid dehydrogenase complexes, catalyses the oxidative-hydrolytic cleavage of acetoin to acetaldehyde and acetyl-CoA in many bacterial strains, both aerobic and anaerobic. The enzyme is composed of multiple copies of three enzymatic components:acetoin oxidoreductase (E1), dihydrolipoamide acetyltransferase (E2) and dihydrolipoyl dehydrogenase (E3).

1  [PMID:2061286]

Priefert H, Hein S, Kruger N, Zeh K, Schmidt B, Steinbuchel A

Identification and molecular characterization of the Alcaligenes eutrophus H16 aco operon genes involved in acetoin catabolism.

J. Bacteriol. 173 (1991) 4056-71.

2  [PMID:8110297]

Oppermann FB, Steinbuchel A

Identification and molecular characterization of the aco genes encoding the Pelobacter carbinolicus acetoin dehydrogenase enzyme system.

J. Bacteriol. 176 (1994) 469-85.

3  [PMID:8206840]

Kruger N, Oppermann FB, Lorenzl H, Steinbuchel A

Biochemical and molecular characterization of the Clostridium magnum acetoin dehydrogenase enzyme system.

J. Bacteriol. 176 (1994) 3614-30.

4  [PMID:7813883]

Huang M, Oppermann FB, Steinbuchel A

Molecular characterization of the Pseudomonas putida 2,3-butanediol catabolic pathway.

FEMS. Microbiol. Lett. 124 (1994) 141-50.

5  [PMID:10368162]

Huang M, Oppermann-Sanio FB, Steinbuchel A

Biochemical and molecular characterization of the Bacillus subtilis acetoin catabolic pathway.

J. Bacteriol. 181 (1999) 3837-41.