KEGG   ENZYME: 2.3.1.192Help
Entry
EC 2.3.1.192                Enzyme                                 

Name
glycine N-phenylacetyltransferase;
arylacetyl-CoA N-acyltransferase;
arylacetyltransferase;
GAT (gene name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
phenylacetyl-CoA:glycine N-phenylacetyltransferase
Reaction(IUBMB)
phenylacetyl-CoA + glycine = CoA + phenylacetylglycine [RN:R05841]
Reaction(KEGG)
Substrate
phenylacetyl-CoA [CPD:C00582];
glycine [CPD:C00037]
Product
CoA [CPD:C00010];
phenylacetylglycine [CPD:C05598]
Comment
Not identical with EC 2.3.1.13 (glycine N-acyltransferase).
This enzyme was purified from bovine liver mitochondria. L-asparagine, L-glutamine and L-arginine are alternative substrates to glycine, but have higher Km values.
History
EC 2.3.1.192 created 2010
Pathway
Phenylalanine metabolism
Orthology
K15517  
glycine N-phenylacetyltransferase
Genes
MMU: 
240549(Gm4952)
RNO: 
309227(Glyatl1)
CGE: 
100767729(Glyat)
NGI: 
HGL: 
OCU: 
TUP: 
CFA: 
AML: 
UMR: 
FCA: 
PTG: 
BTA: 
280801(GAT)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
OBI: 
 » show all
Taxonomy
Reference
1  [PMID:457678]
  Authors
Nandi DL, Lucas SV, Webster LT Jr.
  Title
Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization.
  Journal
J. Biol. Chem. 254 (1979) 7230-7.
Reference
2  [PMID:2283662]
  Authors
Kelley M, Vessey DA
  Title
The effects of ions on the conjugation of xenobiotics by the aralkyl-CoA and arylacetyl-CoA N-acyltransferases from bovine liver mitochondria.
  Journal
J. Biochem. Toxicol. 5 (1990) 125-35.
Reference
3  [PMID:9664233]
  Authors
Vessey DA, Lau E
  Title
Determination of the sequence of the arylacetyl acyl-CoA:amino acid N-acyltransferase from bovine liver mitochondria and its homology to the aralkyl  acyl-CoA:amino acid N-acyltransferase.
  Journal
J. Biochem. Mol. Toxicol. 12 (1998) 275-9.
  Sequence
[bta:280801]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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