KEGG   ENZYME: 2.3.1.192Help
Entry
EC 2.3.1.192                Enzyme                                 

Name
glycine N-phenylacetyltransferase;
arylacetyl-CoA N-acyltransferase;
arylacetyltransferase;
GAT (gene name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
phenylacetyl-CoA:glycine N-phenylacetyltransferase
Reaction(IUBMB)
phenylacetyl-CoA + glycine = CoA + phenylacetylglycine [RN:R05841]
Reaction(KEGG)
Substrate
phenylacetyl-CoA [CPD:C00582];
glycine [CPD:C00037]
Product
CoA [CPD:C00010];
phenylacetylglycine [CPD:C05598]
Comment
Not identical with EC 2.3.1.13 (glycine N-acyltransferase).
This enzyme was purified from bovine liver mitochondria. L-asparagine, L-glutamine and L-arginine are alternative substrates to glycine, but have higher Km values.
History
EC 2.3.1.192 created 2010
Pathway
ec00360  Phenylalanine metabolism
Orthology
K15517  glycine N-phenylacetyltransferase
Genes
MMU: 240549(Gm4952)
RNO: 309227(Glyatl1)
CGE: 100767729(Glyat)
NGI: 103733339
HGL: 101711041
CCAN: 109678085
OCU: 100353150
TUP: 102491601
CFA: 483462
AML: 100477175
UMR: 103666138
ORO: 101370540
FCA: 101098257
PTG: 102966488
BTA: 280801(GAT)
BOM: 102284675
BIU: 109569853
PHD: 102339162
CHX: 102175783
OAS: 101108949
SSC: 100517803
CFR: 102512072
CDK: 105094919
BACU: 103014180
LVE: 103084684
OOR: 101287278
ECB: 100068389
EPZ: 103556887
EAI: 106825140
MYB: 102251191
MYD: 102768664
OBI: 106867414
 » show all
Taxonomy
Reference
1  [PMID:457678]
  Authors
Nandi DL, Lucas SV, Webster LT Jr.
  Title
Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization.
  Journal
J. Biol. Chem. 254 (1979) 7230-7.
Reference
2  [PMID:2283662]
  Authors
Kelley M, Vessey DA
  Title
The effects of ions on the conjugation of xenobiotics by the aralkyl-CoA and arylacetyl-CoA N-acyltransferases from bovine liver mitochondria.
  Journal
J. Biochem. Toxicol. 5 (1990) 125-35.
Reference
3  [PMID:9664233]
  Authors
Vessey DA, Lau E
  Title
Determination of the sequence of the arylacetyl acyl-CoA:amino acid N-acyltransferase from bovine liver mitochondria and its homology to the aralkyl  acyl-CoA:amino acid N-acyltransferase.
  Journal
J. Biochem. Mol. Toxicol. 12 (1998) 275-9.
  Sequence
[bta:280801]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.192
IUBMB Enzyme Nomenclature: 2.3.1.192
ExPASy - ENZYME nomenclature database: 2.3.1.192
BRENDA, the Enzyme Database: 2.3.1.192

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