KEGG   ENZYME: 2.3.1.198Help
Entry
EC 2.3.1.198                Enzyme                                 

Name
glycerol-3-phosphate 2-O-acyltransferase;
sn-2-glycerol-3-phosphate O-acyltransferase;
glycerol-3-phosphate O-acyltransferase (ambiguous)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acyl-CoA:sn-glycerol 3-phosphate 2-O-acyltransferase
Reaction(IUBMB)
an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate [RN:R06872]
Reaction(KEGG)
Substrate
acyl-CoA [CPD:C00040];
sn-glycerol 3-phosphate [CPD:C00093]
Product
CoA [CPD:C00010];
2-acyl-sn-glycerol 3-phosphate [CPD:C03974]
Comment
A membrane-associated enzyme required for suberin or cutin synthesis in plants. Active with a wide range of acyl-CoA substrates (C16:0-C24:0). The enzyme from some sources has much higher activity with omega-oxidized acyl-CoAs. Some enzymes are bifunctional and have an additional phosphatase activity producing sn-2-monoacylglycerols.
History
EC 2.3.1.198 created 2012
Pathway
Glycerophospholipid metabolism
Biosynthesis of secondary metabolites
Orthology
K13508  
glycerol-3-phosphate acyltransferase
Genes
ATH: 
AT1G01610(GPAT4) AT1G02390(GPAT2) AT1G06520(GPAT1) AT2G38110(GPAT6) AT3G11430(GPAT5) AT4G00400(GPAT8) AT4G01950(GPAT3) AT5G06090(GPAT7)
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LJA: 
Lj0g3v0047509.1(Lj0g3v0047509.1) Lj0g3v0189079.1(Lj0g3v0189079.1) Lj0g3v0263249.1(Lj0g3v0263249.1) Lj0g3v0263249.2(Lj0g3v0263249.2) Lj1g3v2301880.1(Lj1g3v2301880.1) Lj1g3v4834040.1(Lj1g3v4834040.1) Lj1g3v4835150.1(Lj1g3v4835150.1) Lj2g3v0345020.1(Lj2g3v0345020.1) Lj2g3v2612020.1(Lj2g3v2612020.1) Lj2g3v3106320.1(Lj2g3v3106320.1) Lj3g3v2340960.1(Lj3g3v2340960.1) Lj5g3v1585220.1(Lj5g3v1585220.1) Lj6g3v0920870.1(Lj6g3v0920870.1) Lj6g3v0920880.1(Lj6g3v0920880.1) Lj6g3v0920880.2(Lj6g3v0920880.2)
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POP: 
POPTR_0002s19350g(POPTRDRAFT_755676) POPTR_0005s22390g(POPTRDRAFT_559475) POPTR_0006s09900g(POPTRDRAFT_560888) POPTR_0008s05840g(POPTRDRAFT_803258) POPTR_0010s20880g(POPTRDRAFT_805502) POPTR_0014s08130g(POPTRDRAFT_834747)
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OSA: 
DOSA: 
Os01t0299300-00(Os01g0299300) Os01t0329000-01(Os01g0329000) Os01t0631400-01(Os01g0631400) Os01t0855000-01(Os01g0855000) Os05t0280500-01(Os05g0280500) Os05t0448300-01(Os05g0448300) Os05t0457800-01(Os05g0457800) Os11t0679700-01(Os11g0679700) Os12t0563000-00(Os12g0563000)
OBR: 
BDI: 
ATS: 
109740321(LOC109740321) 109743316(LOC109743316) 109744567(LOC109744567) 109745940(LOC109745940) 109751148(LOC109751148) 109756848(LOC109756848) 109760226(LOC109760226) 109762257(LOC109762257) 109766754(LOC109766754) 109770082(LOC109770082) 109770085(LOC109770085) 109771224(LOC109771224) 109771542(LOC109771542) 109778965(LOC109778965) 109783055(LOC109783055)
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 » show all
Taxonomy
Reference
1  [PMID:20551224]
  Authors
Yang W, Pollard M, Li-Beisson Y, Beisson F, Feig M, Ohlrogge J
  Title
A distinct type of glycerol-3-phosphate acyltransferase with sn-2 preference and  phosphatase activity producing 2-monoacylglycerol.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 107 (2010) 12040-5.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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