KEGG   ENZYME: 2.3.1.200Help
Entry
EC 2.3.1.200                Enzyme                                 

Name
lipoyl amidotransferase;
LipL (gene name, ambiguous)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
[glycine cleavage system H]-N6-lipoyl-L-lysine:[lipoyl-carrier protein]-N6-L-lysine lipoyltransferase
Reaction(IUBMB)
[glycine cleavage system H]-N6-lipoyl-L-lysine + a [lipoyl-carrier protein] = glycine cleavage system H + a [lipoyl-carrier protein]-N6-lipoyl-L-lysine
Substrate
[glycine cleavage system H]-N6-lipoyl-L-lysine;
[lipoyl-carrier protein]
Product
glycine cleavage system H;
[lipoyl-carrier protein]-N6-lipoyl-L-lysine
Comment
In the bacterium Listeria monocytogenes the enzyme takes part in a pathway for scavenging of lipoic acid. The enzyme is bound to 2-oxo-acid dehydrogenases such as the pyruvate dehydrogenase complex, where it transfers the lipoyl moiety from lipoyl-[glycine cleavage system H] to the E2 subunits of the complexes.
History
EC 2.3.1.200 created 2012
Orthology
K18821  
lipoyl amidotransferase
Genes
VIR: 
LMO: 
LMF: 
LMH: 
LMC: 
LMN: 
LMY: 
LMT: 
LMG: 
LMS: 
LMJ: 
LMQ: 
LML: 
LMP: 
LMW: 
LMX: 
LMZ: 
LMON: 
LMOC: 
LMOS: 
LMOO: 
LMOY: 
LMOT: 
LMOA: 
LMOL: 
LMOG: 
LMOE: 
LMOB: 
LMOJ: 
LMOZ: 
LMOD: 
LMOW: 
LMOX: 
LMOQ: 
LMR: 
LMOK: 
LMV: 
LMOM: 
LIN: 
LWE: 
lwe2516(lplA)
LSG: 
LIV: 
LII: 
LIW: 
LIA: 
LIO: 
 » show all
Taxonomy
Reference
1  [PMID:21768091]
  Authors
Christensen QH, Hagar JA, O'Riordan MX, Cronan JE
  Title
A complex lipoate utilization pathway in Listeria monocytogenes.
  Journal
J. Biol. Chem. 286 (2011) 31447-56.
  Sequence
[lmo:lmo2566]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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