KEGG   ENZYME: 2.3.1.204Help
Entry
EC 2.3.1.204                Enzyme                                 

Name
octanoyl-[GcvH]:protein N-octanoyltransferase;
LipL;
octanoyl-[GcvH]:E2 amidotransferase;
ywfL (gene name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
[glycine cleavage system H]-N6-octanoyl-L-lysine:[lipoyl-carrier protein]-N6-L-lysine octanoyltransferase
Reaction(IUBMB)
[glycine cleavage system H]-N6-octanoyl-L-lysine + a [lipoyl-carrier protein] = glycine cleavage system H + a [lipoyl-carrier protein]-N6-octanoyl-L-lysine
Substrate
[glycine cleavage system H]-N6-octanoyl-L-lysine;
[lipoyl-carrier protein]
Product
glycine cleavage system H;
[lipoyl-carrier protein]-N6-octanoyl-L-lysine
Comment
In the bacterium Bacillus subtilis it has been shown that the enzyme catalyses the
amidotransfer of the octanoyl moiety from [glycine cleavage system H]-N6-octanoyl-L-lysine (i.e. octanoyl-GcvH) to the E2 subunit (dihydrolipoamide acetyltransferase) of pyruvate dehydrogenase.
History
EC 2.3.1.204 created 2012
Orthology
K16869  octanoyl-[GcvH]:protein N-octanoyltransferase
Genes
BSU: BSU37640(ywfL)
BSR: I33_3912
BSL: A7A1_0183
BSH: BSU6051_37640(ywfL)
BSY: I653_18465
BSUT: BSUB_04000
BSUL: BSUA_04000(lipL)
BSUS: Q433_20735
BSS: BSUW23_18590(ywfL)
BST: GYO_4150
BSO: BSNT_10422(ywfL)
BSQ: B657_37640(lipL)
BSX: C663_3669
BLI: BL03912(ywfL)
BLD: BLi03988(lipL)
BLH: BaLi_c40020(ywfL)
BAY: RBAM_034820(ywfL)
BAQ: BACAU_3511(ywfL)
BYA: BANAU_3664(ywfL)
BAMP: B938_17870
BAML: BAM5036_3412(lipL)
BAMA: RBAU_3620(lipL)
BAMN: BASU_3396(lipL)
BAMB: BAPNAU_3678(ywfL)
BAMT: AJ82_19655
BAMY: V529_37540(ywfL)
BMP: NG74_03657(lipL)
BAO: BAMF_3595(ywfL)
BAZ: BAMTA208_19045(ywfL)
BQL: LL3_03907
BXH: BAXH7_03899(ywfL)
BQY: MUS_4141(ywfL)
BAMI: KSO_001650
BAMC: U471_36270
BAMF: U722_18605
BATR: TD68_15735
BHA: BH3822
BAN: BA_5635
BAR: GBAA_5635
BAT: BAS5237
BAI: BAA_5662
BANT: A16_56470
BANR: A16R_57150
BANS: BAPAT_5402
BANV: DJ46_4282
BCE: BC5386
BCA: BCE_5515
BCZ: BCE33L5084(lplA)
BCQ: BCQ_5227(lplA)
BCX: BCA_5537
BAL: BACI_c53810(lplA3)
BNC: BCN_5314
BCF: bcf_27045
BCER: BCK_08425
BTK: BT9727_5067(lplA)
BTL: BALH_4885(lplA)
BTT: HD73_5799
BTHI: BTK_28580
BTM: MC28_4619(lipL)
BTG: BTB_c55860(lipL)
BTI: BTG_21455
BTW: BF38_1109
BWW: bwei_4397(lipL)
BMYC: DJ92_2474
BMYO: BG05_623
BCL: ABC3909
BPU: BPUM_3400
BPUM: BW16_18070
BPUS: UP12_17525
BMQ: BMQ_5201
BMD: BMD_5187
BMH: BMWSH_0078(lplA)
BMEG: BG04_2195
BCK: BCO26_2848(lplA)
BAG: Bcoa_1407
BCOA: BF29_2108
BJS: MY9_3854
BMET: BMMGA3_16260(lipL)
BACW: QR42_17075
BACP: SB24_11285
BACB: OY17_01075
BACO: OXB_1381
BACY: QF06_17260
BACL: BS34A_40820(ywfL)
BALM: BsLM_3794
BEO: BEH_23685
BGY: BGLY_4392
BKW: BkAM31D_24735(lipL)
BBEV: BBEV_0116(lipL)
OIH: OB3021
GKA: GK3414
GTN: GTNG_3360
GEA: GARCT_03398(lipL)
AFL: Aflv_2759
AAMY: GFC30_310
AXL: AXY_20760
LSP: Bsph_0948
BSE: Bsel_3218
SAU: SA0546
SAV: SAV0589
SAW: SAHV_0587
SAM: MW0544
SAS: SAS0548
SAR: SAR0595
SAC: SACOL0635
SAX: USA300HOU_0582(lplA2)
SAE: NWMN_0552
SAD: SAAV_0551
SUE: SAOV_0623
SUJ: SAA6159_00542(lplA2)
SUK: SAA6008_00596(lplA2)
SUC: ECTR2_542
SUZ: MS7_0578(lipL)
SUG: SAPIG0663
SAUA: SAAG_01011
SAUS: SA40_0530
SAUU: SA957_0545
SAUG: SA268_0543
SAUT: SAI1T1_2004530(lipL)
SAUJ: SAI2T2_1004550(lipL)
SAUK: SAI3T3_1004540(lipL)
SAUQ: SAI4T8_1004530(lipL)
SAUV: SAI7S6_1004540(lipL)
SAUW: SAI5S5_1004500(lipL)
SAUX: SAI6T6_1004510(lipL)
SAUY: SAI8T7_1004540(lipL)
SAB: SAB0539
SAUB: C248_0664
SAUM: BN843_5820
SAUC: CA347_604(lipL)
SAUR: SABB_00638
SAUI: AZ30_02975
SAUD: CH52_02815
SAUF: X998_0630(lipL)
SAMS: NI36_02935
SEP: SE0360
SER: SERP0237
SEPP: SEB_00282
SEPS: DP17_1667
SHA: SH2403
SHH: ShL2_02198(lplA2)
SSP: SSP2123
SCA: SCA_0243(lplA)
SDT: SPSE_2176
SPAS: STP1_1675
SXO: SXYL_02259(lipL)
SHU: SHYC_10710(lipL)
SCAP: AYP1020_2339(lipL)
SSCH: LH95_10280
SSCZ: RN70_11015
SAGQ: EP23_11450
MCL: MCCL_1832
MCAK: MCCS_23790(lipL)
ESI: Exig_0238
EAN: Eab7_0224(lipL)
PPY: PPE_00707
PPM: PPSC2_03960(ywfL)
PPO: PPM_0737(ywfL)
PPOL: X809_03500
PPQ: PPSQR21_007660(lplA)
PPOY: RE92_08025
PMW: B2K_30315
PLV: ERIC2_c27590(lipL)
PSAB: PSAB_02365
PRI: PRIO_0673
ASOC: CB4_01192(lipL)
BTS: Btus_0765
SIV: SSIL_3429
JEO: JMA_31000
EFA: EF1144
EFL: EF62_1594
EFS: EFS1_0971
EFQ: DR75_215
EFM: M7W_926
EHR: EHR_08305
ENE: ENT_05690
ECAS: ECBG_02767
EMU: EMQU_2023
EDU: LIU_11235
MPX: MPD5_0934
CRN: CAR_c02920(ywfL)
CARC: NY10_1994
JDA: BW727_101697(lipL)
LPIL: LIP_1085
 » show all
Taxonomy
Reference
1  [PMID:21338421]
  Authors
Christensen QH, Martin N, Mansilla MC, de Mendoza D, Cronan JE
  Title
A novel amidotransferase required for lipoic acid cofactor assembly in Bacillus subtilis.
  Journal
Mol. Microbiol. 80 (2011) 350-63.
  Sequence
[bsu:BSU37640]
Reference
2  [PMID:21338420]
  Authors
Martin N, Christensen QH, Mansilla MC, Cronan JE, de Mendoza D
  Title
A novel two-gene requirement for the octanoyltransfer reaction of Bacillus subtilis lipoic acid biosynthesis.
  Journal
Mol. Microbiol. 80 (2011) 335-49.
  Sequence
[bsu:BSU37640]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.204
IUBMB Enzyme Nomenclature: 2.3.1.204
ExPASy - ENZYME nomenclature database: 2.3.1.204
BRENDA, the Enzyme Database: 2.3.1.204

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