| Entry |
|
|---|
| Name |
2-acylglycerol O-acyltransferase;
acylglycerol palmitoyltransferase;
monoglyceride acyltransferase;
acyl coenzyme A-monoglyceride acyltransferase;
monoacylglycerol acyltransferase |
|---|
| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
 |
|---|
| Sysname |
acyl-CoA:2-acylglycerol O-acyltransferase |
|---|
| Reaction(IUBMB) |
acyl-CoA + 2-acylglycerol = CoA + diacylglycerol [RN:R01368] |
|---|
| Reaction(KEGG) |
R01368 > R03838;
(other) R03755 R03756
 |
|---|
| Substrate |
acyl-CoA [CPD:C00040];
2-acylglycerol [CPD:C02112] |
|---|
| Product |
CoA [CPD:C00010];
diacylglycerol [CPD:C00165] |
|---|
| Comment |
Various 2-acylglycerols can act as acceptor; palmitoyl-CoA and other
long-chain acyl-CoAs can act as donors. The sn-1 position and the
sn-3 position are both acylated, at about the same rate. |
|---|
| Pathway |
ec00561 Glycerolipid metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4016575]
Manganaro F, Kuksis A.
Purification and preliminary characterization of 2-monoacylglycerol
acyltransferase from rat intestinal villus cells.
Can. J. Biochem. Cell. Biol. 63 (1985) 341-7.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.3.1.22
IUBMB Enzyme Nomenclature: 2.3.1.22
ExPASy - ENZYME nomenclature database: 2.3.1.22
BRENDA, the Enzyme Database: 2.3.1.22
CAS: 9055-17-8 |
|---|
