KEGG   ENZYME: 2.3.1.227Help
Entry
EC 2.3.1.227                Enzyme                                 

Name
GDP-perosamine N-acetyltransferase;
perB (gene name);
GDP-alpha-D-perosamine N-acetyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acetyl-CoA:GDP-4-amino-4,6-dideoxy-alpha-D-mannose N-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + GDP-4-amino-4,6-dideoxy-alpha-D-mannose = CoA + GDP-4-acetamido-4,6-dideoxy-alpha-D-mannose [RN:R10514]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
GDP-4-amino-4,6-dideoxy-alpha-D-mannose [CPD:C20638]
Product
CoA [CPD:C00010];
GDP-4-acetamido-4,6-dideoxy-alpha-D-mannose [CPD:C20672]
Comment
D-Perosamine is one of several dideoxy sugars found in the O-antigen component of the outer membrane lipopolysaccharides of Gram-negative bacteria.
History
EC 2.3.1.227 created 2013
Pathway
Amino sugar and nucleotide sugar metabolism
Orthology
K17939  
GDP-perosamine N-acetyltransferase
Genes
ECE: 
Z3192(wbdR)
ECS: 
ETW: 
ECSP_2781(wbdR)
ELX: 
Taxonomy
Reference
1  [PMID:18201574]
  Authors
Albermann C, Beuttler H
  Title
Identification of the GDP-N-acetyl-d-perosamine producing enzymes from Escherichia coli O157:H7.
  Journal
FEBS. Lett. 582 (2008) 479-84.
  Sequence
[ece:Z3192] [ecs:ECs2831]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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