KEGG   ENZYME: 2.3.1.229Help
Entry
EC 2.3.1.229                Enzyme                                 

Name
4-coumaroyl-homoserine lactone synthase;
p-coumaryl-homoserine lactone synthase;
RpaI
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
4-coumaroyl-CoA:S-adenosyl-L-methionine trans-4-coumaroyltranserase (lactone-forming, methylthioadenosine-releasing)
Reaction(IUBMB)
4-coumaroyl-CoA + S-adenosyl-L-methionine = CoA + S-methyl-5'-thioadenosine + N-(4-coumaroyl)-L-homoserine lactone [RN:R10529]
Reaction(KEGG)
Substrate
4-coumaroyl-CoA [CPD:C00223];
S-adenosyl-L-methionine [CPD:C00019]
Product
CoA [CPD:C00010];
S-methyl-5'-thioadenosine [CPD:C00170];
N-(4-coumaroyl)-L-homoserine lactone [CPD:C20677]
Comment
The enzyme is found in the bacterium Rhodopseudomonas palustris, which produces N-(4-coumaroyl)-L-homoserine lactone as a quorum-sensing signal.
History
EC 2.3.1.229 created 2013
Orthology
K18096  
acyl-homoserine lactone synthase
Genes
MLO: 
MCI: 
MOP: 
MAM: 
MES: 
HOE: 
AAK: 
AVI: 
RLE: 
pRL100164(rhiI)
RLU: 
RHL: 
BJA: 
BJU: 
BJP: 
BRA: 
BBT: 
BRS: 
AOL: 
BRC: 
RPA: 
RPB: 
RPC: 
RPD: 
RPE: 
RPT: 
RPX: 
NWI: 
NHA: 
OCA: 
OCG: 
OCO: 
MEX: 
MEA: 
MDI: 
MCH: 
MRD: 
MET: 
MPO: 
MNO: 
MOR: 
MOC_6267(solI)
META: 
MAQU: 
CHEL: 
BVR: 
MCG: 
PZU: 
HBA: 
NPP: 
NPN: 
SPHK: 
SPHP: 
SGI: 
SPHM: 
SSAN: 
SCH: 
SSY: 
SYB: 
SBD: 
SPMI: 
TMO: 
TMO_c0698(rhlI)
 » show all
Taxonomy
Reference
1  [PMID:18563084]
  Authors
Schaefer AL, Greenberg EP, Oliver CM, Oda Y, Huang JJ, Bittan-Banin G, Peres CM, Schmidt S, Juhaszova K, Sufrin JR, Harwood CS
  Title
A new class of homoserine lactone quorum-sensing signals.
  Journal
Nature. 454 (2008) 595-9.
  Sequence
[rpa:RPA0320]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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